A Multimodal Training Modulates Short Afferent Inhibition and Improves Complex Walking in a Cohort of Faller Older Adults With an Increased Prevalence of Parkinson's Disease

Pelosin Elisa; Cerulli Cecilia; Ogliastro Carla; Lagravinese Giovanna; Mori Laura; Bonassi Gaia; Mirelman Anat; Hausdorff Jeffrey M.; Abbruzzese Giovanni; Marchese Roberta; Avanzino Laura

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A Multimodal Training Modulates Short Afferent Inhibition and Improves Complex Walking in a Cohort of Faller Older Adults With an Increased Prevalence of Parkinson's Disease

机译：多峰训练调节短传感抑制，并改善了较卑鄙的老年人的复杂，帕金森病的普遍率增加

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Background: Falls are frequent in Parkinson's disease and aging. Impairments in the cholinergic-mediated attentional supervision of gait may contribute to increased fall risk, especially when obstacles challenge gait. Interventions combining motor-cognitive approaches have been shown to improve motor performance, cognitive skills, and falls number. Here, we hypothesized that an intervention simulating an attention-demanding walking condition could affect not only complex gait performance and fall risk but also short-latency afferent inhibition (SAI), as a marker of cholinergic activity.

机译：背景：瀑布在帕金森病和老龄化中经常出现。胆碱能介导的障碍的损伤介导的步态可能有助于增加危险的风险，特别是当障碍攻击步态时。结合电动机认知方法的干预措施已经显示出改善电机性能，认知技能和跌倒号码。在这里，我们假设模拟注意力的行走条件的干预不仅可能影响复杂的步态性能和落下风险，而且可能影响短期的传入抑制（SAI），作为胆碱能活性的标志物。

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来源
《The journals of gerontology.Series A. Biological sciences and medical sciences》 |2020年第4期|共7页
作者
Pelosin Elisa; Cerulli Cecilia; Ogliastro Carla; Lagravinese Giovanna; Mori Laura; Bonassi Gaia; Mirelman Anat; Hausdorff Jeffrey M.; Abbruzzese Giovanni; Marchese Roberta; Avanzino Laura;
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作者单位

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

Univ Genoa Sect Human Physiol Dept Expt Med Genoa Italy;

Tel Aviv Sourasky Med Ctr Dept Neurol Ctr Study Movement Cognit &

Mobil Tel Aviv Israel;

Tel Aviv Sourasky Med Ctr Dept Neurol Ctr Study Movement Cognit &

Mobil Tel Aviv Israel;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet &

Maternal Genoa Italy;

IRCSS Osped Policlin San Martino Genoa Italy;

IRCSS Osped Policlin San Martino Genoa Italy;

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原文格式 PDF
正文语种 eng
中图分类老年病学;
关键词
Aging; Falls; Cholinergic system; Treadmill training; Virtual reality;

机译：老化;瀑布;胆碱能系统;跑步机训练;虚拟现实;

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1. A Multimodal Training Modulates Short Afferent Inhibition and Improves Complex Walking in a Cohort of Faller Older Adults With an Increased Prevalence of Parkinson's Disease [J] . Pelosin Elisa, Cerulli Cecilia, Ogliastro Carla, The journals of gerontology.Series A. Biological sciences and medical sciences . 2020,第4期

机译：多峰训练调节短传感抑制，并改善了较卑鄙的老年人的复杂，帕金森病的普遍率增加
2. Combination of rTMS and treadmill training modulates corticomotor inhibition and improves walking in parkinson disease: A randomized trial [J] . YangY.-R., TsengC.-Y., ChiouS.-Y., Neurorehabilitation and neural repair . 2013,第1期

机译：一项随机试验将rTMS与跑步机训练相结合可调节皮层运动抑制并改善帕金森氏病的行走
3. Repetitive transcranial magnetic stimulation combined with treadmill training can modulate corticomotor inhibition and improve walking performance in people with Parkinson's disease [J] . Margaret K.Y. Mak Journal of physiotherapy . 2013,第2期

机译：重复经颅磁刺激结合跑步机训练可以调节帕金森氏病患者的皮质激素抑制并改善步行表现
4. Prevalence of hypertension increases exponentially with proximity to roadways in an adult cardiac catheterination cohort [C] . Ward-Caviness Cavin, Colette Blach, Carol Haynes, Annual conference of the International Society of Exposure Science . 2014

机译：在成人心脏导管插入队列中，高血压的发病率随着靠近道路的增加呈指数增长
5. The brain mechanisms underlying walking in complex situations in healthy older adults and persons with parkinson's disease. [D] . Maidan, Inbal. 2015

机译：在健康的老年人和帕金森氏病患者中，复杂情况下行走的大脑机制。
6. The efficacy of treadmill training with and without projected visual context for improving walking ability and reducing fall incidence and fear of falling in older adults with fall-related hip fracture: a randomized controlled trial [O] . Mariëlle W. van Ooijen, Melvyn Roerdink, Marga Trekop, 2016

机译：带有或不带有预期视觉环境的跑步机训练在提高与摔倒相关的髋部骨折的老年人中的步行能力降低摔倒发生率和跌倒恐惧的功效：一项随机对照试验
7. Repetitive transcranial magnetic stimulation combined with treadmill training can modulate corticomotor inhibition and improve walking performance in people with Parkinson's disease [O] . Mak Margaret K.Y. 2013

机译：反复经颅磁刺激结合跑步机训练可以调节帕金森氏病患者的皮质激素抑制并改善步行性能

A Multimodal Training Modulates Short Afferent Inhibition and Improves Complex Walking in a Cohort of Faller Older Adults With an Increased Prevalence of Parkinson's Disease

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