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Incidence and In-Hospital Outcomes of Patients Presenting With Stent Thrombosis (from the Japanese Nationwide Percutaneous Coronary Intervention Registry)

机译:患有支架血栓形成的患者的发病率和住院后结果(来自日本全国范围的经皮冠状动脉介入登记处)

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摘要

Clinical presentation of stent thrombosis (ST) and its sequela under contemporary practice have not been fully elucidated largely due to rare incidence of ST. We sought to assess the characteristics in patients with clinical presentation of ST and their in-hospital outcomes, utilizing nationwide registration system for percutaneous coronary interventions (J-PCI). The present study included acute coronary syndrome (ACS) patients undergoing PCI with clinical findings of definite ST from January 2014 to December 2016. Patients' characteristics, in-hospital mortality and its composite with periprocedural complications were evaluated. Full match comparison was performed. During the study period, 256,610 ACS patients (37.9% of total PCI cases) underwent PCI and 1,367 ST patients (1.9%) were identified from 73,241 ACS patients' records who had a history of previous PCI. Overall, patients with ST were younger but had higher incidence of previous myocardial infarction, compared with those without. In addition, ST patients had increased rate of crude in-hospital death (4.8% vs 1.1%, p <0.001). After full match comparison, the incidence of recurrent ST (post-PCI) was significantly higher in ST patients when compared with ACS patients presenting without ST (4.3% vs 0.9%, p <0.001). Despite younger age, patients with ST had significantly higher incidence of in-hospital mortality and cardiovascular complications, including recurrent ST, compared with those without. (C) 2019 Elsevier Inc. All rights reserved.
机译:在当代实践下,支架血栓形成(ST)及其后遗症的临床介绍尚未在很大程度上完全阐明,因为ST的罕见发病率很大。我们试图评估ST及其在医院后果的临床介绍患者的特征,利用全国范围的注册系统进行经皮冠状动脉干预(J-PCI)。本研究包括急性冠状动脉综合征(ACS)接受PCI的患者,从2014年1月到2016年1月到2016年12月,评估患者的特征,医院内死亡率及其具有霸王性并发症的复合性。进行全面匹配比较。在研究期间,256,610名ACS患者(37.9%的PCI案例中的37.9%)从患有以前PCI的历史记录的73,241名ACS患者记录中确定了PCI和1,367例ST患者(1.9%)。总体而言,与ST的患者更年轻,但与那些没有。此外,ST患者的粗疗患者患者含量增加(4.8%vs 1.1%,p <0.001)。在完全匹配比较后,与没有ST的ACS患者的ACS患者相比,在ST患者的复发性ST(PCI)的发生率显着高(4.3%Vs 0.9%,P <0.001)。尽管年龄较小,但患有患者的入院性死亡率和心血管并发症的发病率明显较高,包括复发性ST。 (c)2019 Elsevier Inc.保留所有权利。

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