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首页> 外文期刊>The American Journal of Cardiology >Relation of Baseline Hemoglobin Level to In-Hospital Outcomes in Patients Who Undergo Percutaneous Coronary Intervention (from a Japanese Multicenter Registry)
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Relation of Baseline Hemoglobin Level to In-Hospital Outcomes in Patients Who Undergo Percutaneous Coronary Intervention (from a Japanese Multicenter Registry)

机译：基线血红蛋白水平与经过经皮冠状动脉干预的患者的医院内结果（来自日本多中心登记处）

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Scarce data exist regarding the relation between baseline hemoglobin and in-hospital outcomes after percutaneous coronary intervention (PCI). We studied 13,010 cases of PCI in a Japanese multicenter registry from 2008 to 2016. Patients were divided into 5 groups according to 2-g/dl increments in their preprocedural hemoglobin (from 10 to 16 g/dl). Patients with lower hemoglobin levels were older and had higher proportions of females and co-morbidities, including diabetes mellitus and renal failure, than those with higher hemoglobin levels. In-hospital complications were observed more frequently in patients with lower than higher levels. After adjustment, baseline hemoglobin was inversely associated with total procedural complications (odds ratio [OR] 0.87, 95% confidence interval [CI] 0.84 to 0.90, p 0.001), in-hospital mortality (OR 0.82, 95% CI 0.77 to 0.87, p 0.001), and bleeding complications (OR 0.93, 95% CI 0.88 to 0.98, p = 0.007). Categorically, reverse J-shaped curvilinear correlations were present between baseline hemoglobin and in-hospital adverse outcomes. When the reference group comprised patients with a baseline hemoglobin of 12 to 14 g/dl, patients within the lowest hemoglobin levels (10 g/dl) were at the highest risk of total procedural complications (OR 2.57, 95% CI 2.07 to 3.17, p 0.001), in-hospital mortality (OR 3.46, 95% CI 2.34 to 5.11, p 0.001), and bleeding complications (OR 2.36, 95% CI 1.70 to 3.25, p 0.001). In subgroup analyses, similar trends were observed in both men and women, and in both patients with acute coronary syndrome and stable coronary artery disease. In conclusion, a low baseline hemoglobin is a simple and powerful predictor of poor outcomes in patients who undergo PCI. (C) 2017 Elsevier Inc. All rights reserved.
机译：存在于经皮冠状动脉干预后基线血红蛋白与医院内后果关系的稀缺数据。我们从2008年至2016年研究了日本多中心注册表中的13,010例PCI。根据其预培养血红蛋白中的2-G / DL增量，患者分为5组（来自10至16g / dl）。血红蛋白水平较低的患者年龄较大，患有更高比例的女性和糖尿病，包括糖尿病和肾功能衰竭，而不是血红蛋白水平较高的糖尿病。在低于更高水平的患者中更频繁地观察到院内并发症。在调整后，基线血红蛋白与总程序并发症（差距率[或] 0.87,95％置信区间隔[CI] 0.84至0.90，P <0.001），内部死亡率（或0.82,95％CI 0.77至0.77 0.87，p <0.001），并出血并发症（或0.93,95％CI 0.88至0.98，p = 0.007）。分散地，基线血红蛋白和医院内不良结果之间存在反向J形曲线相关性。当参考组包括基线血红蛋白为12-14克/ DL的患者时，最低血红蛋白水平（10g / dl）的患者处于总程序并发症的最高风险（或2.57,95％CI 2.07至3.17，P <0.001），内部死亡率（或3.46,95％CI 2.34至5.11，P <0.001），以及出血并发症（或2.36,95％CI 1.70至3.25，P <0.001）。在亚组分析中，男性和女性观察到类似的趋势，以及急性冠状动脉综合征和稳定的冠状动脉疾病的患者。总之，低基线血红蛋白是一种简单而强大的预测因素，对接受PCI的患者的差异。 （c）2017年Elsevier Inc.保留所有权利。

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