...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Impact of Self-Reported Family History of Premature Cardiovascular Disease on the Outcomes of Patients Hospitalized for Acute Coronary Syndrome (from the Acute Coronary Syndrome Israel Survey [ACSIS] 2000 to 2013)
【24h】

Impact of Self-Reported Family History of Premature Cardiovascular Disease on the Outcomes of Patients Hospitalized for Acute Coronary Syndrome (from the Acute Coronary Syndrome Israel Survey [ACSIS] 2000 to 2013)

机译：自我报告的家庭历史对急性冠状动脉综合征住院患者的患者的结果（来自急性冠状动脉综合征以色列调查[ACSIS] 2000至2013）

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Family history of premature cardiovascular disease (FHpCVD) is a well-established risk factor for development of coronary artery disease. However, little is known about the impact of FHpCVD on the outcome of patients presenting with acute coronary syndrome (ACS). We therefore aimed to evaluate the outcomes of ACS patients grouped by the presence and/or absence of FHpCVD. All patients ≤65 at admission who had an ACS event and were enrolled in the national ACS Israel Survey registry from 2000 to 2013 were included. Patients were grouped by the presence or absence of self-reported FHpCVD. Nearest neighbor propensity score matching was applied to create an evenly matched cohort of patients. Outcomes included 30-day MACE (defined as the composite of death, unstable angina pectoris, myocardial infarction, stroke, stent thrombosis, and urgent revascularization) and its individual components. Of 7,173 ACS patients, 33.9% reported FHpCVD. These patients were younger, with lower prevalence of diabetes, previous cerebrovascular and kidney diseases, but had higher prevalence of smoking and hyperlipidemia (p <0.001 for each). The propensity score-matching cohort included 1,793 pairs of evenly matched patients. The rate of 30-day MACE did not differ in the groups, as well as 1-year mortality (2.4% vs 2.2%, with vs without FHpCVD, respectively). During long-term follow-up (median 7.6 years), mortality rate was lower in the FHpCVD group (hazard ratio 0.82, 95% confidence intervals 0.69 to 0.99). In conclusion, we observed no differences in short- and intermediate-term outcomes based on the presence and/or absence of FHpCVD. However, patients with FHpCVD had better long-term survival.
机译：早产心血管疾病（FHPCVD）的家族史是一种既有良好的冠状动脉疾病发展的危险因素。然而，关于FHPCVD对患有急性冠状动脉综合征（ACS）的患者结果的影响很少。因此，我们旨在评估通过FHPCVD的存在和/或不存在分组的ACS患者的结果。包括ACS事件的入学患者≤65患者，并于2000年至2013年入选国家ACS以色列调查登记处。通过自我报告的FHPCVD存在或不存在患者进行分组。最近的邻居倾向得分匹配用于创造均匀匹配的患者队列。结果包括30天的爵士（定义为死亡，不稳定的心绞痛，心肌梗塞，中风，支架血栓形成和紧急血运重建）及其个体组分。 7,173例ACS患者，报告的FHPCVD报告33.9％。这些患者年轻，糖尿病患病率较低，患有脑血管和肾脏疾病的患病率较低，但吸烟和高脂血症的患病率较高（每次P <0.001）。倾向分数匹配的队列包括1,793对均匀匹配的患者。 30天智慧的速度在群体中没有差异，以及1年死亡率（2.2％vs 2.2％，分别没有FHPCVD的VS）。在长期随访（中位数7.6岁）期间，FHPCVD组的死亡率较低（危险比0.82,95％置信区间0.69至0.99）。总之，我们观察到基于FHPCVD的存在和/或不存在的短期和中期结果没有差异。然而，FHPCVD的患者具有更好的长期存活。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号