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首页> 外文期刊>AIDS care. >The epidemiology of HIV-1 infection in northern Tanzania: results from a community-based study.
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The epidemiology of HIV-1 infection in northern Tanzania: results from a community-based study.

机译：坦桑尼亚北部HIV-1感染的流行病学：一项基于社区的研究结果。

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We conducted a community-based study to determine the predictors of HIV-1 among women aged 20-44 years (N = 1,418) and their regular male partners (N = 566) from randomly selected households in Moshi, Tanzania. The weighted prevalence of HIV-1 was 10.3% in women and 7% in men. The highest risk of HIV-1 was in subjects whose partners were HIV-1 seropositive in both women (adjusted odds ratio (AOR) = 26.63; 95% confidence interval (CI): 10.74-66.02) and men (AOR = 22.25; 95%CI: 7.06-70.15). Herpes simplex virus type 2 (HSV-2) and Mycoplasma genitalium were also significantly associated with HIV-1. Women with male partners >or=12 years older than themselves had increased risk of HIV-1 (AOR = 1.99; 95%CI: 1.01-7.85). Other predictors of HIV-1 were history of infertility and the number of sex partners in the last three years in women and the age at time of circumcision and history of past sexually transmitted diseases (STDs) in male partners. These findings show that HIV-1/STDs were major public health problems among women and their long-term partners in this population. HIV-1 prevention efforts should include promotion of couple's HIV-1 counseling and testing services, control of HSV-2, promotion of safer sexual practices and strategies to reduce the age difference between women and their partners.
机译：我们进行了一项基于社区的研究，从坦桑尼亚莫希的随机选择的家庭中确定20-44岁的女性（N = 1,418）及其正常男性伴侣（N = 566）中HIV-1的预测因子。女性的HIV-1加权患病率为10.3％，男性为7％。 HIV-1的最高风险发生在两名女性（调整后的优势比（AOR）= 26.63; 95％置信区间（CI）：10.74-66.02）和男性（AOR = 22.25; 95）中，其伴侣均为HIV-1血清阳性的受试者中。 ％CI：7.06-70.15）。 2型单纯疱疹病毒（HSV-2）和生殖器支原体也与HIV-1显着相关。男性伴侣年龄大于或等于12岁的女性患HIV-1的风险增加（AOR = 1.99; 95％CI：1.01-7.85）。 HIV-1的其他预测因素包括女性不育史，最近三年的性伴侣数量，包皮环切术时的年龄以及男性伴侣的过去性传播疾病史。这些发现表明，HIV-1 / STD是该人群中妇女及其长期伴侣的主要公共卫生问题。预防HIV-1的工作应包括促进夫妻的HIV-1咨询和检测服务，控制HSV-2，促进更安全的性行为以及减少女性与其伴侣之间年龄差异的策略。

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