• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>AIDS care. >Strategies for management and treatment of dyslipidemia in HIV/AIDS.
【24h】

Strategies for management and treatment of dyslipidemia in HIV/AIDS.

机译：艾滋病毒/血脂异常的管理和治疗策略。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

With the improved survival of HIV-infected patients, there are increased concerns about the long-term effects of treatment, including protease inhibitor (PI)-related dyslipidemia. Some 50-70% of patients receiving combination antiretroviral therapy (ART) involving PIs develop lipid abnormalities consisting of elevated levels of total cholesterol, low-density lipoprotein cholesterol and triglycerides that are well-known risk factors for cardiovascular disease. Treatment of HIV dyslipidemia should include lifestyle modifications such as a low-fat diet, increased exercise, reduced alcohol consumption and smoking cessation. In many patients, however, these changes alone will not correct lipid levels. In some patients, changing the PI component of ART to another PI or non-PI and/or lipid-lowering drugs has proven successful. Each approach is associated with advantages and limitations and the need to maintain viral suppression must be balanced with the need to treat abnormal lipid levels.
机译：随着HIV感染患者生存期的改善，人们越来越关注治疗的长期效果，包括蛋白酶抑制剂（PI）相关的血脂异常。接受PI的联合抗逆转录病毒疗法（ART）的患者中约有50-70％会出现脂质异常，包括总胆固醇，低密度脂蛋白胆固醇和甘油三酸酯含量升高，这些都是心血管疾病的众所周知的危险因素。 HIV血脂异常的治疗应包括改变生活方式，例如低脂饮食，增加运动，减少饮酒和戒烟。但是，在许多患者中，仅这些改变就不能纠正血脂水平。在某些患者中，将ART的PI成分更改为其他PI或非PI和/或降脂药物已被证明是成功的。每种方法都有其优点和局限性，维持病毒抑制的需求必须与治疗异常血脂水平相平衡。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号