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Reproductive intentions and family planning practices of pregnant HIV-infected Malawian women on antiretroviral therapy

机译:感染艾滋病毒的马拉维孕妇怀孕期接受抗逆转录病毒疗法的生殖意图和计划生育实践

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The objective of this study was to describe the pregnancy intentions of pregnant HIV-infected Malawian women on antiretroviral therapy (ART) for at least 6 months prior to the current pregnancy, and to assess whether time on ART was associated with pregnancy intention. We conducted a cross-sectional analysis of HIV-infected Malawian women receiving antenatal care at a government hospital with a survey assessing ART history, reproductive history, and family planning use at conception. We used Pearson's chi-square tests and Fisher's exact tests to compare these parameters between women on ART greater than 24 months with those on ART less than 24 months. Modified Poisson regression was performed to assess the association between time on ART and pregnancy intention. Most women (75%) reported that their current pregnancy was unintended, defined as either Mistimed (21%) or Unwanted (79%). Women on ART for longer than 2 years were more likely to report an unintended pregnancy (79% versus 65%, p=.03), though there was no significant association between time on ART and pregnancy intention in multivariate analysis. Most women (79%) were using contraception at the time of conception, with condoms being most popular (91%), followed by injectables (9%) and the implant (9%). HIV-infected women on ART continue to experience high rates of unintended pregnancy in the Option B+ era. As Option B+ continues to be implemented in Malawi and increasing numbers of HIV-infected women initiate lifelong ART, ensuring that the most effective forms of contraception are accessible is necessary to decrease unintended pregnancy.
机译:这项研究的目的是描述在当前妊娠前至少6个月接受HIV感染的马拉维孕妇的抗逆转录病毒疗法(ART)的怀孕意向,并评估接受ART的时间是否与怀孕意向相关。我们在一家政府医院对接受艾滋病毒感染的马拉维妇女进行产前检查进行了横断面分析,并进行了一项调查,以评估受孕时的ART史,生殖史和计划生育使用情况。我们使用Pearson的卡方检验和Fisher精确检验来比较接受24个月以上抗逆转录病毒治疗的女性和接受24个月以上抗逆转录病毒治疗的女性的这些参数。进行修正的泊松回归以评估抗逆转录病毒治疗时间与怀孕意愿之间的关联。大多数女性(75%)报告说,他们目前的怀孕是意外的,定义为误时(21%)或不想要的(79%)。接受抗逆转录病毒治疗超过2年的女性更有可能报告意外怀孕(79%比65%,p = .03),尽管在多变量分析中抗逆转录病毒治疗时间与怀孕意向之间没有显着关联。大多数妇女(79%)在受孕时使用避孕药具,其中最流行的是安全套(91%),其次是注射剂(9%)和植入物(9%)。在方案B +时代,接受抗逆转录病毒治疗的受HIV感染的妇女继续意外怀孕的比例很高。随着在马拉维继续实施备选方案B +,以及越来越多的艾滋病毒感染妇女开始终生抗病毒治疗,为减少意外怀孕,必须确保可获得最有效的避孕方法。

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