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首页> 外文期刊>AIDS care. >Factors associated with abandonment of infants born to HIV-positive women: results from a Ukrainian birth cohort.
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Factors associated with abandonment of infants born to HIV-positive women: results from a Ukrainian birth cohort.

机译：与艾滋病毒呈阳性妇女的婴儿遗弃有关的因素：乌克兰出生队列的结果。

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Social marginalisation and other challenges facing HIV-positive pregnant women in Ukraine may put them at increased risk of relinquishing their infants to the state. We described rates of infant abandonment (exclusive non-parental care to most recent follow-up, censored at two years of age) and investigated associated factors using logistic regression models, in 4759 mother-infant pairs enrolled across six Ukrainian sites in the European Collaborative Study from 2000 to May 2009. Median maternal age was 26.0 years, 81.8% were married or cohabiting and 60.6% were nulliparous at enrolment. An injecting drug use (IDU) history was reported by 18.4%, 80.2% took antiretroviral therapy (ART) antenatally and most deliveries were vaginal. A small but significant proportion of infants had been cared for exclusively in institutions by their second birthday (2.1% overall), decreasing from 3.8% (15/393) in 2000-2002 to 1.6% (49/3136) in 2006-2009 (p<0.01), concurrent with prevention of mother-to-child transmission scale-up. A further 1% of infants spent some time in non-parental care. Antenatal ART was associated with an 88% reduced abandonment risk (adjusted odds ratio (AOR) 0.12), versus receipt of single dose nevirapine only, and this was reflected in HIV infection prevalence in the two groups (17.1% of abandoned infants versus 6.6% in parental care). Mothers without a cohabiting partner or husband were more likely to abandon (AOR 4.08), as were active IDUs (AOR 3.27) and those with >/=1 previous children (AOR 1.89 for second-born and AOR 2.56 for subsequent births). Women delivering by elective caesarean section were less likely to abandon (AOR 0.37 versus vaginal), as were those leaving full-time education later (AOR 0.61 for 17-18 years versus /=19 years versus
机译：乌克兰的艾滋病毒呈阳性孕妇面临社会边缘化和其他挑战，这可能会使她们面临将婴儿遗弃该州的更大风险。我们描述了在欧洲合作组织的六个乌克兰站点登记的4759对母婴中，婴儿的遗弃率（最近一次随访中的独家非父母护理，在2岁时进行了检查），并使用logistic回归模型调查了相关因素。从2000年至2009年5月进行的研究。孕产妇的中位年龄为26.0岁，已婚或同居为81.8％，入学时未生育为60.6％。据报道，注射用药（IDU）的病史为18.4％，产前服用抗逆转录病毒疗法（ART）的为80.2％，大多数分娩是通过阴道进行的。一小部分但相当大比例的婴儿在其第二个生日之前仅在机构接受照料（总体占2.1％），从2000-2002年的3.8％（15/393）降至2006-2009年的1.6％（49/3136）（ p <0.01），同时防止母婴传播扩大。另有1％的婴儿花了一些时间在非父母照料中。与仅接受单剂量奈韦拉平相比，产前ART与放弃风险降低88％（调整后的优势比（AOR）0.12）相关，这反映在两组的HIV感染率中（两组分别为17.1％和6.6％）在父母照料中）。没有同居伴侣或丈夫的母亲更容易放弃（AOR 4.08），活跃的IDU（AOR 3.27）以及以前有> / = 1个孩子的母亲（第二胎为AOR 1.89，第二胎为AOR 2.56）。选择性剖腹产的妇女放弃的可能性较小（AOR 0.37 vs阴道），较晚时离开全日制的妇女（17-18岁的AOR 0.61 vs / = 19岁的AOR 0.23与

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