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首页> 外文期刊>AIDS care. >Correlates of adherence to combination antiretroviral therapy among members of HIV-positive mixed status couples.
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Correlates of adherence to combination antiretroviral therapy among members of HIV-positive mixed status couples.

机译：在HIV阳性混合身份夫妇中，坚持联合抗逆转录病毒疗法的相关性。

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摘要

This exploratory study assessed medication adherence and its correlates in HIV-positive members of HIV mixed status couples. Forty couples were interviewed; the HIV-positive participants consisted of 19 gay men, 14 heterosexual men and seven heterosexual women. Mean self-reported adherence (over the past three days) for the whole sample was 95%; the mean adherence rate for gay men (99%) was significantly higher (p < 0.05) than that of heterosexual men (94%) and heterosexual women (87%) based on a ranked transformation of the adherence score. In analyses involving measures rated by the HIV-positive partner, higher adherence was associated with more years of education, greater perceived treatment efficacy, stronger belief that combination therapy is a significant advancement in treatment, and greater knowledge of HIV treatments and consequences of poor adherence. Higher adherence was associated with the HIV-negative partner attributing less risk to unprotected anal/vaginal sex within the couple, while lower adherence was associated with a greater likelihood that the couple engaged in unprotected anal/vaginal sex in the last two months. A larger sample is needed to substantiate these findings.
机译：这项探索性研究评估了药物混合状态夫妇中HIV阳性成员的药物依从性及其相关性。采访了四十对夫妇。艾滋病毒阳性参与者包括19名男同性恋者，14名异性恋男人和7名异性恋女人。整个样本的自我报告遵守率（过去三天）为95％;根据依从度得分的排名转换，男同性恋者的平均依从率（99％）显着高于异性恋男人（94％）和异性恋女性（87％）（p <0.05）。在涉及由HIV阳性伴侣评估的措施的分析中，依从性越高，受教育年限越长;感知到的治疗效果越高;更坚信联合疗法是治疗的重大进步;对HIV治疗的更多了解以及依从性差的后果。较高的依从性与艾滋病毒阴性伴侣将夫妻中未保护的肛交/阴道性行为的风险降低相关，而较低的依从性与夫妻在过去两个月中进行未保护的肛交/阴道性交的可能性更高。需要更大的样本量来证实这些发现。

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