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Mother to child transmission of HIV in Vitoria, Brazil: Factors associated with lack of HIV prevention.

机译:在巴西维多利亚,艾滋病毒的母婴传播:与缺乏艾滋病毒预防有关的因素。

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Screening HIV infection in pregnancy provides an ideal opportunity to make an early diagnosis in women in order to provide treatment to reduce vertical transmission to the newborn. The objectives were to describe the profile of HIV-infected pregnant women attending municipal hospitals in Vitoria and to identify the causes associated with the lack of HIV therapeutic prophylaxis. Descriptive analysis of antenatal and HIV surveillance data of pregnant women in Vitoria, Brazil from 1997 to 2001 was performed. HIV infection was reported in 208 pregnant women. Their median age was 23 years, antenatal care was reported in 96.2% and HIV infection was diagnosed during antenatal care in 60.1%. Zidovudine (ZDV) therapy was initiated in 88% of the cases, 57.9% of which started before 20 weeks of gestation. The remaining 12% of the total of pregnant women received no therapy. Factors associated with lack of mother to child transmission (MTCT) prevention were: test not available (14 cases), delay of test result (seven cases) and patient's refusal to take medication (four cases). After delivery, 8.2% of the newborn did not receive ZDV and 14 women breastfed. Among the 196 live births, 3.1% (95%CI 1.9-4.3) of MTCT was reported. These data from an area with comprehensive HIV and antenatal surveillance provide an opportunity to identify gaps in public health efforts to reduce MTCT.
机译:在孕妇中筛查HIV感染提供了一个理想的机会,可以对妇女进行早期诊断,从而提供治疗方法以减少对新生儿的垂直传播。目的是描述在维多利亚市立医院就诊的感染艾滋病毒的孕妇的概况,并查明缺乏预防性治疗艾滋病毒的相关原因。对1997年至2001年巴西维多利亚州孕妇的产前和HIV监测数据进行描述性分析。据报告208名孕妇感染了艾滋病毒。他们的中位年龄为23岁,据报道产前护理占96.2%,在产前护理期间诊断出HIV感染的占60.1%。齐多夫定(ZDV)治疗在88%的病例中开始,其中57.9%在妊娠20周之前开始。其余12%的孕妇未接受任何治疗。缺乏预防母婴传播(MTCT)的相关因素包括:无法进行检测(14例),检测结果延迟(7例)和患者拒绝服药(4例)。分娩后,有8.2%的新生儿未接受ZDV,有14名妇女进行了母乳喂养。在196例活产婴儿中,据报道有3.1%(95%CI 1.9-4.3)的MTCT。来自艾滋病毒和产前监测全面地区的这些数据提供了一个机会,可以发现在减少MTCT的公共卫生工作中的差距。

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