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HIV infection in families of HIV-positive and 'at-risk' HIV-negative women.

机译：HIV阳性和“高危” HIV阴性妇女家庭中的HIV感染。

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Research of HIV infection within the family has focused upon sexual partners and vertical transmission. The scope of the problem of multiple infections and clustering of HIV among family members has, thus far, been less extensively explored. The objectives of this study are to investigate HIV infection in family members of HIV-seropositive and HIV-seronegative high-risk women and to consider the impact of multiple HIV infections within the family. Baseline data were evaluated from a prospective observational cohort of 871 HIV-seropositive and 439 seronegative at-risk women who are participants in a longitudinal study of HIV in women at four sites in the USA (Montefiore, Bronx, NY; Johns Hopkins University, Baltimore, MD; Brown University, Providence, RI; Wayne State University, Detroit, MI). Women were asked if anyone close to them had HIV/AIDS or had died from HIV/AIDS. Responses which included HIV-positive family members were analyzed. In the seropositive cohort, 35% (307/871) of the women had a family member with HIV infection. Of these 307 women, 38% reported having a sibling, 24% a husband and 27% had more than one family member with HIV/AIDS. Forty-nine per cent of Latina women, 34% of black women, and 21% of white women reported having a family member with HIV/AIDS. Using logistic regression analysis, we found that Latina and black women were significantly more likely than white women to have a sibling, extended family member or more than one family member with HIV/AIDS. Compared to seropositive women, seronegative high-risk women enrolled in this study appear equally likely to have an HIV-infected family member. In this study of HIV-positive women and high-risk seronegative women, a third reported having multiple family members with HIV infection, most often in a sibling. The high prevalence of HIV within families, particularly in the families of Latina and black women, mandates attention in planning both prevention and care.
机译：家庭中艾滋病毒感染的研究集中在性伴侣和垂直传播上。到目前为止，家庭成员之间多重感染和HIV聚集的问题范围还没有得到广泛的探讨。这项研究的目的是调查艾滋病毒血清阳性和艾滋病毒阴性高危妇女家庭成员的艾滋病毒感染情况，并考虑家庭中多种艾滋病毒感染的影响。基线数据是根据前瞻性观察队列中的871名HIV血清阳性和439名血清阴性的高危妇女而进行的评估，这些妇女参加了美国四个地方的HIV纵向研究的参与者（美国纽约州布朗克斯市蒙泰菲奥;巴尔的摩约翰霍普金斯大学，马里兰州;布朗大学，罗德岛州普罗维登斯;韦恩州立大学，密歇根州底特律。妇女被问及与她们亲近的人是否患有艾滋病毒/艾滋病或死于艾滋病毒/艾滋病。分析了包括艾滋病毒阳性家庭成员在内的回应。在血清阳性人群中，35％（307/871）的妇女有家庭成员感染了艾滋病毒。在这307名妇女中，有38％的人报告有兄弟姐妹，有24％的丈夫是丈夫，有27％的艾滋病毒/艾滋病有多于一名家庭成员。报告说有49％的拉丁裔妇女，34％的黑人妇女和21％的白人妇女报告说自己的家庭成员患有艾滋病毒/艾滋病。使用逻辑回归分析，我们发现拉丁裔和黑人妇女比同龄白人妇女拥有同胞，大家庭成员或感染艾滋病毒/艾滋病的家庭成员多得多。与血清反应阳性妇女相比，参加这项研究的血清阴性高危妇女似乎也有可能感染了艾滋病毒。在这项针对HIV阳性妇女和高危血清阴性妇女的研究中，三分之一的人报告有多个家庭成员感染了HIV，多数情况下是在同胞中。家庭中，尤其是在拉丁裔和黑人妇女的家庭中，艾滋病毒的流行很高，因此在规划预防和护理时必须引起注意。

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