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首页> 外文期刊>AIDS care. >Antiretroviral treatments used among adults with HIV infection in Europe.
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Antiretroviral treatments used among adults with HIV infection in Europe.

机译：在欧洲，艾滋病毒感染者使用抗逆转录病毒疗法。

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摘要

International guidelines for the treatment of human immunodeficiency virus (HIV) infection change rapidly. They are mainly based on results from large-scale randomized clinical trials, but also on hypotheses. The objective of the study was to look at the use of antiretrovirals (ARVs) in different HIV treatment centres in Europe. Between August 1996 and September 1997 self-administered anonymous questionnaires were distributed to persons with HIV infection at inpatient and outpatient departments in 11 European countries; 1,366 people completed the questionnaire. Important differences in use of ARVs were noted between different centres. Zidovudine was the drug that was used predominantly in all countries and by 77% of all patients; the use of didanosine, zalcitabine and stavudine differed widely. Use of ARVs was found to be lower for people who reported intravenous drug use (compared to homosexual transmission), people with a low education level, and those with a monthly income lower than 992 Euro. The use of a protease inhibitor containing ARV treatment regimen was significantly lower in the centres in the south of Europe. Between 1996 and 1997, many persons with HIV infection in Europe received a suboptimal ARV treatment regimen. Use of ARVs should be improved for intravenous drug users, persons with lower educational level and lower income.
机译：治疗人类免疫缺陷病毒（HIV）感染的国际准则迅速变化。它们主要基于大规模随机临床试验的结果，也基于假设。该研究的目的是研究在欧洲不同的HIV治疗中心使用抗逆转录病毒药物（ARV）的情况。在1996年8月至1997年9月期间，向欧洲11个国家的住院和门诊部门的艾滋病毒感染者分发了自我管理的匿名问卷; 1,366人完成了问卷。注意到不同中心之间在使用抗逆转录病毒药物方面存在重要差异。齐多夫定是所有国家/地区中主要使用的药物，占所有患者的77％;地那洛辛，扎西他滨和司他夫定的使用差异很大。据发现，报告静脉注射毒品（与同性恋传播相比），文化程度较低的人和月收入低于992欧元的人，抗逆转录病毒药物的使用率较低。在欧洲南部的中心地区，使用含有ARV治疗方案的蛋白酶抑制剂的使用率明显降低。在1996年至1997年之间，欧洲许多艾滋病毒感染者接受了次优的ARV治疗方案。对于静脉吸毒者，教育程度较低和收入较低的人，应改善ARV的使用。

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