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首页> 外文期刊>AIDS care. >Which factors hinder the decision of Polish HIV-positive patients to take up antiretroviral therapy?
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Which factors hinder the decision of Polish HIV-positive patients to take up antiretroviral therapy?

机译：哪些因素阻碍波兰HIV阳性患者决定接受抗逆转录病毒治疗？

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The implementation of highly active antiretroviral therapy (HAART) in 1996 has significantly reduced mortality and morbidity for HIV-positive patients worldwide. However not all eligible persons start HAART. To identify reasons for therapy refusal by HIV-positive persons we performed a questionnaire study. The investigation was conducted among 321 HIV-positive individuals and focused on the decision to take up antiretroviral treatment. Out of 71 untreated patients, 34 (47.9%) admitted that in their case the therapy was not indicated, whereas 20 (28.3%) were afraid of potential side effects that might change their appearance, e.g. face lipoatrophy. Only the treated patients had been prepared to take up therapy, although 17 patients (6.0%) had not received any explanation of the therapy principles, aims or necessity to comply with medication regime. The therapy is generally not discussed with the patients for whom it is not currently indicated, which may contribute to the fixation of fears and prejudices. Doctors who treat HIV-positive patients should be aware of the prejudices and fears their patients have towards antiretroviral therapy in order to react properly and by means of the available antiretroviral drugs help prolong life and improve its quality.
机译：1996年实施的高效抗逆转录病毒疗法（HAART）大大降低了全球HIV阳性患者的死亡率和发病率。但是，并非所有符合条件的人都可以启动HAART。为了确定HIV阳性者拒绝治疗的原因，我们进行了问卷调查。该调查是在321名HIV阳性患者中进行的，重点是采取抗逆转录病毒治疗的决定。在71位未接受治疗的患者中，有34位（47.9％）承认在他们的病例中未进行治疗，而20位（28.3％）担心可能会改变其外观的潜在副作用，例如面部脂肪萎缩。尽管只有17名患者（6.0％）没有接受任何有关治疗原则，目的或必要性的依从性解释，但只有接受治疗的患者才准备接受治疗。通常不与目前尚无适应症的患者讨论该疗法，这可能有助于解决恐惧和偏见。治疗HIV阳性患者的医生应了解偏见，并担心他们的患者会接受抗逆转录病毒治疗以使其正确反应，并通过可用的抗逆转录病毒药物帮助延长寿命并改善其质量。

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