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首页> 外文期刊>AIDS care. >The impact of substance dependence on HIV sexual risk-reduction among men with severe mental illness.
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The impact of substance dependence on HIV sexual risk-reduction among men with severe mental illness.

机译：严重精神疾病患者中物质依赖对降低HIV性风险的影响。

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摘要

We explored the impact of substance dependence on the efficacy of an HIV sexual risk reduction intervention previously shown to be effective among men with severe mental illness by comparing rates of high-risk sexual behaviors among men with (n=26) and without (n=31) a lifetime history of substance dependence. We sub-divided subjects by alcohol and drug dependence status, comparing each intervention sub-group to the corresponding control sub-group. At each follow-up interval (six, 12 and 18 months), the intervention group as a whole and the non-substance dependent participants showed a significant reduction in risk; the substance-dependent men showed no difference from controls. These data suggest that among men with severe mental illness, substance dependence may be a further impediment to HIV risk reduction.
机译：我们通过比较有（n = 26）和没有（n = 26）的男性高风险性行为的发生率，探讨了物质依赖对先前显示的对患有严重精神疾病的男性有效的降低HIV性风险的干预措施的影响。 31）一生依赖药物的历史。我们按酒精和药物依赖状态将受试者细分，将每个干预亚组与相应的对照组进行比较。在每个随访间隔（六个月，十二个月和十八个月），整个干预组和非药物依赖参与者的风险均显着降低。依赖物质的男性与对照组没有差异。这些数据表明，在患有严重精神疾病的男性中，物质依赖可能会进一步阻碍降低HIV风险。

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