Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier.

Woodman Z; Mlisana K; Treurnicht F; Abrahams MR; Thebus R; Karim SA; Williamson C

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Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier.

机译：与十年前的队列研究相比，短暂的交流降低了南非C型亚型感染妇女双重感染的发生率。

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Previously, we determined the incidence of dual infections in a South African cohort and its association with higher viral setpoint. Ten years later, we compare the incidence and impact of dual infections at transmission on viral setpoint in a geographically similar cohort (n = 46) making use of both the heteroduplex mobility assay (HMA) and the more recent single genome amplification (SGA) approach. HIV incidence was lower in this cohort (7% compared to 18%), and we find a similar reduction in the number of dual infections (9% compared to 19%). Unlike the previous study, there was no association between either dual infection (n = 4) or multivariant transmission (n = 7) and disease progression. This study emphasized the importance of monitoring changes in the HIV epidemic as it may have important ramifications on our understanding of the natural history of disease.

机译：以前，我们确定了南非队列中双重感染的发生率及其与较高病毒设定值的关系。十年后，我们使用异源双链迁移率分析（HMA）和最新的单基因组扩增（SGA）方法，在地理相似的队列（n = 46）中比较了传播过程中双重感染对病毒设定点的发生率和影响。。在这一队列中，艾滋病毒的发病率较低（7％，而18％），并且我们发现双重感染的数量也有类似的下降（9％，而19％）。与先前的研究不同，双重感染（n = 4）或多变量传播（n = 7）与疾病进展之间没有关联。这项研究强调了监测HIV流行变化的重要性，因为它可能会对我们对疾病自然史的理解产生重要影响。

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《AIDS Research and Human Retroviruses》 |2011年第11期|共6页
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Woodman Z; Mlisana K; Treurnicht F; Abrahams MR; Thebus R; Karim SA; Williamson C;
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1. Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier. [J] . Woodman Z, Mlisana K, Treurnicht F, AIDS Research and Human Retroviruses . 2011,第11期

机译：与十年前的队列研究相比，短暂的交流降低了南非C型亚型感染妇女双重感染的发生率。
2. Rapid Disease Progression in HIV-1 Subtype C-Infected South African Women [J] . Mlisana Koleka, Werner Lise, Garrett Nigel J., Clinical infectious diseases . 2014,第9期

机译：HIV-1亚型C感染南非女性的快速疾病进展
3. Evaluation of Two Commercially Available, Inexpensive Alternative Assays Used for Assessing Viral Load in a Cohort of Human Immunodeficiency Virus Type 1 Subtype C-Infected Patients from South Africa [J] . G. Stevens, N. Rekhviashvili, L. E. Scott, Journal of Clinical Microbiology . 2005,第2期

机译：评估用于评估来自南非的人类免疫缺陷病毒1型C型亚型感染人群的病毒载量的两种市售廉价治疗方法的评估
4. Evolving Approaches to Estimate Risks of Transfusion-Transmitted Viral Infections: Incidence-Window Period Model after Ten Years [C] . M.P. Busch International Association for Biologicals International Conference on Advances in Transfusion Safety . 2007

机译：不断发展的估算输血传播病毒感染风险的方法：十年后发生型窗口期模型
5. Putting trust on the line: Implementing telecommunication reform in South Africa and the role of international trade. The first five years. [D] . Cohen, Tracy. 2004

机译：放心线上：在南非实施电信改革和国际贸易的作用。前五年。
6. Short Communication Decreased Incidence of Dual Infections in South African Subtype C-Infected Women Compared to a Cohort Ten Years Earlier [O] . Zenda Woodman, Koleka Mlisana, Florette Treurnicht, -1

机译：与十年前的队列研究相比短期交流降低了南非C型亚型感染妇女双重感染的发生率
7. Short Communication Decreased Incidence of Dual Infections in South African Subtype C-Infected Women Compared to a Cohort Ten Years Earlier [O] . Zenda Woodman, Koleka Mlisana, Florette Treurnicht, 2011

机译：南非亚型C感染妇女的短期通信减少了两年前的队列（南非亚型C感染妇女发病率

Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier.

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