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首页> 外文期刊>AIDS Research and Human Retroviruses >Localization of Productively Infected Cetts in the Spleen and Peyer's Patches of Rhesus Macaques During Acute Infection with SIVmac239Anef-Enhanced Green Fluorescent Protein
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Localization of Productively Infected Cetts in the Spleen and Peyer's Patches of Rhesus Macaques During Acute Infection with SIVmac239Anef-Enhanced Green Fluorescent Protein

机译：SIVmac239Anef增强绿色荧光蛋白急性感染期间恒河猴的脾脏和淋巴集结中生产性感染的ett的定位

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In the spleen and Peyer' s patches, most of these productively infected cells were localized to secondary lymphoid follicles. The infected cells were mostly distributed at the edge of germinal centers. As shown in Fig. la and b, most of the infected cells (green) were colocalized in the peanut agglutinin (PNA)~+ area, which is indicative of germinal centers. Since most of the cells in germinal centers should be undergoing proliferation or differentiation, cells were labeled for Ki67 anitbody to further delineate the germinal centers. As shown in Fig. lc and d, the infected cells (green) were distributed in an area positive for Ki67 (red), which confirmed the above results. Of note, although rare, a few infected cells expressing Ki67 were observed (arrowhead).
机译：在脾和Peyer氏斑中，大多数这些受感染的细胞大部分位于次级淋巴滤泡中。被感染的细胞大部分分布在生发中心的边缘。如图1a和1b所示，大多数被感染的细胞（绿色）共定位在花生凝集素（PNA）+区域，这指示生发中心。由于生发中心中的大多数细胞都应进行增殖或分化，因此将细胞标记为Ki67抗体，以进一步描绘生发中心。如图1c和1d所示，感染的细胞（绿色）分布在对Ki67阳性的区域（红色），这证实了上述结果。值得注意的是，尽管很少见，但观察到一些表达Ki67的感染细胞（箭头）。

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