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首页> 外文期刊>AIDS Research and Human Retroviruses >The Effect of a Structured Exercise Program on Nutrition and Fitness Outcomes in Human Immunodeficiency Virus-Infected Children
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The Effect of a Structured Exercise Program on Nutrition and Fitness Outcomes in Human Immunodeficiency Virus-Infected Children

机译：结构化运动计划对人类免疫缺陷病毒感染儿童营养和健身结局的影响

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摘要

The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training program followed by an unsupervised home-based maintenance program. Outcome measurements included muscular strength/endurance, flexibility, relative peak VO_2, body composition, and lipids. Seventeen subjects (eight females) with a median age of 15.0 years (range: 6.0-22.6) and BMI z-score of 0.61 (range: -1.70-2.57) at entry completed the intervention. After 24 training sessions, the median increases in muscular strength were between 8% and 50%, depending on muscle group. The median increases in muscle endurance, relative peak VO_2, and lean body mass were 38.7% (95% CI: 12.5-94.7; p = 0.006), 3.0ml/kg/min (95% CI: 1.5-6.0; p < 0.001), and 4.5% (95% CI: 2.4-6.6; p < 0.001), respectively. Twelve children completed the home-based maintenance program. Median changes in these outcomes between completion of the hospital-based intervention and a follow-up after completion of the home-based program were near zero. No adverse events occurred during the intervention. A supervised hospital-based fitness program is feasible, safe, and effective for improving general fitness and strength as well as lean body mass in children with HIV.
机译：评估了一项以医院为基础的运动训练计划，然后是一项以家庭为基础的计划，以提高感染艾滋病毒的儿童和青少年的健身，力量和身体成分的变化的可行性和有效性。受试者参加了非随机的24节，医院监督的运动训练计划，然后参加了无监督的家庭维护计划。结果测量包括肌肉力量/耐力，柔韧性，相对峰值VO_2，身体组成和脂质。入选时年龄中位数为15.0岁（范围：6.0-22.6）且BMI z得分为0.61（范围：-1.70-2.57）的17名受试者（八名女性）完成了干预。经过24次训练后，肌肉力量的中位数增加介于8％和50％之间，具体取决于肌肉组。肌肉耐力，相对峰值VO_2和瘦体重的中位数增加为38.7％（95％CI：12.5-94.7; p = 0.006），3.0ml / kg / min（95％CI：1.5-6.0; p <0.001 ）和4.5％（95％CI：2.4-6.6; p <0.001）。十二个孩子完成了家庭维护计划。在完成基于医院的干预与完成基于家庭的计划之后的随访之间，这些结果的中位变化接近于零。干预期间未发生不良事件。在医院监督下进行的健身计划是可行，安全和有效的，可提高HIV感染儿童的总体健身和强度以及瘦体重。

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