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首页> 外文期刊>AIDS care. >A pilot study of the effects of a behavioural intervention on treatment adherence in HIV-infected patients.
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A pilot study of the effects of a behavioural intervention on treatment adherence in HIV-infected patients.

机译：行为干预对HIV感染患者依从性的影响的初步研究。

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A pilot study was carried out in a group of six HIV-infected non-adherent men testing the effects of a behavioural medication management intervention on adherence with antiretroviral drugs. The study was prospective, using a one-group repeated-measures design. Adherence was measured using two self-reports. The intervention was a behaviourally-based programme that lasted for three months and included individualized education about antiretroviral medication and their side effects; positive reinforcement and encouragement; individualized counselling weekly; follow-up calls; and lifestyle assessment and the identification of adherence barriers. Assessments were carried out at recruitment, immediately after the initiation of the intervention, one month, three months and six months later. Results suggested that the intervention enhanced adherence rates from a mean percentage of 80.27 at baseline to a mean of 97.5% at the end of follow-up (six months time point). Similar improvement was observed in the scoresof the scale measuring adherence difficulties. Further, CD4+ counts also slightly improved. Interviews with four of the participants at the end of the study highlighted the problems experienced by patients in taking their medication and supported the usefulness of the intervention. Because of the complexity of the factors behind adherence, it is important that patients are supported with individualized medication management programmes.
机译：在一组六名感染了艾滋病毒的非依恋男性中进行了一项初步研究，测试了行为药物管理干预措施对抗逆转录病毒药物依从性的影响。这项研究是前瞻性的，采用了一组重复测量的设计。使用两个自我报告测量粘附力。干预是基于行为的计划，持续了三个月，其中包括有关抗逆转录病毒药物及其副作用的个性化教育。积极加强和鼓励;每周进行个性化咨询;跟进电话;以及生活方式评估和遵守障碍的识别。干预开始后，一个月，三个月和六个月后立即在招募时进行评估。结果表明，干预措施将依从率从基线时的平均百分比80.27提高到随访结束时（六个月时间点）的平均97.5％。在衡量依从困难程度的量表分数中也观察到了类似的改善。此外，CD4 +计数也略有提高。在研究结束时对四名参与者的访谈强调了患者在服药过程中遇到的问题，并支持了干预措施的有用性。由于依从性背后因素的复杂性，重要的是要为患者提供个性化的药物管理计划。

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