Nuclear Receptors in Cancer Inflammation and Immunity

Zhao Linjie; Hu Hongbo; Gustafsson Jan-Ake; Zhou Shengtao

首页> 外文期刊>Trends in immunology >Nuclear Receptors in Cancer Inflammation and Immunity

【24h】

Nuclear Receptors in Cancer Inflammation and Immunity

机译：癌症炎症和免疫核受体

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Members of the nuclear receptor (NR) superfamily orchestrate cellular processes that can impact on numerous cancer hallmarks. NR activity plays important roles in the tumor microenvironment by controlling inflammation and immune responses. We summarize recent insights into the diverse mechanisms by which NR activity can control tumor inflammation, the roles of different NRs in modulating tumor immunity, and the biological features of immune cells that express specific NRs in the context of cancer. NR-dependent alterations in tumor inflammation and immunity may be amenable to pharmacological manipulation and offer new clues regarding the development of novel cancer therapeutic regimens.

机译：核受体的成员（NR）超家族协调会对众多癌症标志影响的细胞过程。 NR活性通过控制炎症和免疫应答在肿瘤微环境中起重要作用。我们概述了NR活性可以控制肿瘤炎症，不同NR在调节肿瘤抗扰度方面的角色以及表达特异性NR在癌症中的免疫细胞的生物学特征的不同机制的洞察。肿瘤炎症和免疫的NR依赖性改变可以适用于药理操纵，并为新型癌症治疗方案的发展提供新的线索。

著录项

来源
《Trends in immunology》 |2020年第2期|共14页
作者
Zhao Linjie; Hu Hongbo; Gustafsson Jan-Ake; Zhou Shengtao;
展开▼
作者单位

Sichuan Univ West China Hosp 2 Key Lab Birth Defects &

Related Dis Women &

Child Dept Obstet &

Sichuan Univ West China Hosp State Key Lab Biotherapy Dept Rheumatol &

Immunol Chengdu Peoples;

Univ Houston Dept Biol &

Biochem Ctr Nucl Receptors &

Cell Signaling Houston TX 77004 USA;

Sichuan Univ West China Hosp 2 Key Lab Birth Defects &

Related Dis Women &

Child Dept Obstet &

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Nuclear Receptors in Cancer Inflammation and Immunity [J] . Zhao Linjie, Hu Hongbo, Gustafsson Jan-Ake, Trends in immunology . 2020,第2期

机译：癌症炎症和免疫核受体
2. Combinatorial roles of nuclear receptors in inflammation and immunity. [J] . Glass CK, Ogawa S Nature reviews Immunology . 2006,第1期

机译：核受体在炎症和免疫中的组合作用。
3. Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells [J] . PapiA., GuarnieriT., StorciG., Cell death and differentiation . 2012,第7期

机译：核受体激动剂对乳腺癌干细胞的炎症依赖性存活产生相反的影响
4. Inflammation and Cancer: Reprogramming the immune microenvironment as an anti-cancertherapeutic strategy [C] . Lisa M. Coussens Annual Meeting of the American Society for Veterinary Clinical Pathology . 2011

机译：炎症和癌症：重新编程免疫微环境作为抗癌治疗策略
5. Pattern Recognition Receptors and Cytokine-Mediated Activation of Human Basophils: A Novel Link between Innate Immunity and Allergic Inflammation. [D] . Qiu, Huaina. 2013

机译：模式识别受体和人类嗜碱性粒细胞的细胞因子介导的激活：先天免疫和过敏性炎症之间的新型联系。
6. TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88–Dependent Nuclear Factor-κB Activation: Single-Nucleotide Polymorphism– and Selective Estrogen Receptor Modulator–Dependent Modification of Inflammation and Immune Response [O] . Ming-Fen Ho, James N. Ingle, Tim Bongartz, -1

机译：TCL1A单核苷酸多态性和雌激素介导的收费受体-MYD88依赖性核因子-κB激活：单核苷酸多态性和选择性雌激素受体调节剂依赖性的炎症和免疫反应修饰。
7. Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells [O] . A Papi, T Guarnieri, G Storci, 2012

机译：核受体激动剂对乳腺癌干细胞的炎症依赖存活率产生反对作用

Nuclear Receptors in Cancer Inflammation and Immunity

摘要

著录项

相似文献

相关主题

期刊订阅