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Seroprevalence and risk factors of Coxiella burnetii infection in cattle in northeast Algeria

机译:东北阿尔及利亚牛Coxiella Burnetii感染的Seroprengalence和危险因素

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A cross-sectional study was conducted to determine the seroprevalence and the risk factors associated with C. burnetii infection in cattle in the state of Setif in northeastern Algeria from March 2016 to April 2018. A total of 678 cows animals aged at least 24 months and belonging to 90 herds were randomly selected. A serum sample from each cow was tested for antibodies against C. burnetii using an indirect enzyme-linked immunosorbent assay (ELISA). A structured questionnaire focusing on risk factors for C. burnetii infection was administered to farm owners involved in the study. The individual animal prevalence was 11.36% (77/678) (95%CI 8.97-13.75%), the herd prevalence was 45.56% (41/90) (95%CI 35.27-55.84%), and the within-herd prevalence ranged from 9.09 to 57.14% (mean 23.71%; Q1 11.11%, Q2 or median 20%, Q3 30%). Multivariable logistic regression analysis revealed that contact with other herds (odds ratio (OR) 1.95, 95 CI 1.12-3.42) and purchased animals (OR 2.05, 95 CI 1.14-3.68) was identified as risk factors for seropositivity to C. burnetii, while the use of disinfectants (OR 0.32, 95 CI 0.14-0.72) was identified as protective factor. The results from the present study indicate that C. burnetii is circulating into cattle herds in the region of Setif in Northeastern of Algeria. It is recommended to implement good hygienic practices and measures of biosecurity to reduce the spread of infection between cattle herds and possible exposure of humans.
机译:进行了横截面研究,以确定2016年3月至2018年4月在东北阿尔及利亚牛牛的牛C. Burnetii感染与C.Burnetii感染相关的血清升迁和危险因素。共有678名牛母猪至少24个月,随机选择属于90群。使用间接酶联免疫吸附测定(ELISA)测试来自每奶母牛的血清样品用于抗C.伯顿菌株。专注于C.Burnetii感染危险因素的结构化问卷对参与该研究的农场所有者进行。个体动物患病率为11.36%(77/678)(95%CI 8.97-13.75%),牛群患病率为45.56%(41/90)(95%CI 35.27-55.84%),其内普遍存在从9.09至57.14%(平均23.71%; Q1 11.11%,Q2或中位数20%,Q3 30%)。多变量逻辑回归分析显示,与其他畜群(OR)1.95,95 CI 1.12-3.42)和购买的动物(或2.05,95ci 1.14-3.68)的接触被鉴定为血清阳性对C.Burnetii的危险因素,同时使用消毒剂(或0.32,95ci 0.14-0.72)被鉴定为保护因子。本研究结果表明,C.Burnetii在阿尔及利亚东北部的结构中循环到牛群中。建议实施良好的卫生实践和生物安全措施,以减少牛群之间感染的传播和人类可能的暴露。

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