A Self-Killing Rabies Virus That Leaves a Trace on the DNA

Menegas William; Uchida Naoshige; Watabe-Uchida Mitsuko

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A Self-Killing Rabies Virus That Leaves a Trace on the DNA

机译：一种自杀的狂犬病病毒，可在DNA上留下痕迹

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Although modified rabies viruses have emerged as a powerful tool for tracing the inputs to genetically defined populations of neurons, the toxicity of the virus has limited its utility. A recent study employed a self-inactivating rabies (SiR) virus that enables recording or manipulation of targeted neurons for months.

机译：虽然改良的狂犬病病毒已经成为追踪转基因的基因定义的神经元的输入的强大工具，但病毒的毒性有限其实用性。最近的一项研究采用了一种自动活化的狂犬病（SIR）病毒，使能够记录或操纵有针对性的神经元数月。

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来源
《Trends in Neurosciences》 |2017年第10期|共3页
作者
Menegas William; Uchida Naoshige; Watabe-Uchida Mitsuko;
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作者单位

Harvard Univ Dept Mol &

Cellular Biol Ctr Brain Sci Cambridge MA 02138 USA;

Harvard Univ Dept Mol &

Cellular Biol Ctr Brain Sci Cambridge MA 02138 USA;

Harvard Univ Dept Mol &

Cellular Biol Ctr Brain Sci Cambridge MA 02138 USA;

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正文语种 eng
中图分类神经病学;
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专利

1. A Self-Killing Rabies Virus That Leaves a Trace on the DNA [J] . Menegas William, Uchida Naoshige, Watabe-Uchida Mitsuko Trends in Neurosciences . 2017,第10期

机译：一种自杀的狂犬病病毒，可在DNA上留下痕迹
2. Transient Expression of Biologically Active Anti-rabies Virus Monoclonal Antibody in Tobacco Leaves [J] . Mona Shafaghi, Somaye Maktoobian, Rhaimeh Rasouli, Iranian Journal of Biotechnology . 2018,第1期

机译：生物活性抗狂犬病病毒单克隆抗体在烟叶中的瞬时表达
3. High level expression of surface glycoprotein of rabies virus in tobacco leaves and its immunoprotective activity in mice [J] . Ashraf S, Singh PK, Yadav DK, Journal of Biotechnology . 2005,第1期

机译：狂犬病毒表面糖蛋白在烟叶中的高表达及其在小鼠中的免疫保护活性
4. Stray Dogs in Bangkok, Thailand: Rabies Virus Infection and Rabies Antibody Prevalence [C] . S. Kasempimolporn, B. Sichanasai, W. Saengseesom, Joint World Organisation for Animal Health/World Health Organization/European Union International Conference "Towards the elimination of rabies in Eurasia" . 2008

机译：迷路狗在曼谷，泰国：狂犬病病毒感染和狂犬病抗体普遍存在
5. The DNA binding domain of a papillomavirus E2 programs a chimeric nuclease to cleave human papillomavirus DNA. [D] . Horner, Stacy Michelle. 2007

机译：乳头瘤病毒E2的DNA结合结构域可对嵌合核酸酶进行编程，以切割人乳头瘤病毒DNA。
6. Transient Expression of Biologically Active Anti-rabies Virus Monoclonal Antibody in Tobacco Leaves [O] . Mona Shafaghi, Somayeh Maktoobian, Rahimeh Rasouli, 2018

机译：生物活性抗狂犬病病毒单克隆抗体在烟叶中的瞬时表达
7. Nuclei purified from cauliflower mosaic virus-infected turnip leaves contain subgenomic, covalently closed circular cauliflower mosaic virus DNAs. [O] . Olszewski, N E, Guilfoyle, T J 1983

机译：从花椰菜花叶病毒感染的萝卜叶中纯化的核含有亚基因组，共价封闭的圆形花椰菜花叶病毒DNA。

A Self-Killing Rabies Virus That Leaves a Trace on the DNA

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