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首页> 外文期刊>Vascular and endovascular surgery >A Unique Case Report on Hypersensitivity Vasculitis as an Allergic Reaction to the Herpes Zoster Vaccine
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A Unique Case Report on Hypersensitivity Vasculitis as an Allergic Reaction to the Herpes Zoster Vaccine

机译：关于过敏血管炎作为与疱疹疫苗的过敏反应的独特案例报告

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摘要

Hypersensitivity vasculitis (HV) or leukocytoclastic vasculitis is a rare small-vessel vasculitis that may occur as a manifestation of the body's extreme allergic reaction to a drug, infection, or other foreign substance. Characterized by the presence of inflammatory neutrophils in vessel walls, HV results in inflammation and damage to blood vessels, primarily in the skin. Histologically, when neutrophils undergo leukocytoclasia and release nuclear debris into the vasculature, vascular damage manifests as palpable purpura. The incidence of HV is unknown and its relationship and interaction with certain vaccinations is rare and poorly understood. Affected patients with HV generally have a good prognosis; however, fatality may occur if organs such as the central nervous system, heart, lungs, or kidneys are involved. We report a unique case of a 60-year-old man who presented with a serious case of HV after receiving the herpes zoster vaccine. A thorough literature review yielded only one similar case of vascular reaction to the varicella vaccine that was reported in the Annals of Internal Medicine in 1997; however, no other reported cases with regard to the herpes zoster vaccine have been found. Our case presents a rare glimpse into HV that may result from varicella vaccine administration.
机译：超敏感性血管炎（HV）或白细胞细胞痉挛性血管炎是一种罕见的小血管血管炎，其可能随着身体对药物，感染或其他异物的极端过敏反应的表现而发生。在血管壁中存在炎性中性粒细胞的存在，HV主要导致炎症和血管损伤，主要在皮肤上。组织学上，当中性粒细胞经历白细胞癌并将核碎片释放到血管系统中，血管损伤表现为可触及的紫癜。 HV的发病率未知，其与某些疫苗接种的关系和相互作用是罕见的，并且理解得很差。受影响的HV患者通常具有良好的预后;然而，如果涉及中枢神经系统，心脏，肺部或肾脏等器官，可能发生死亡。我们报告了一个60岁男子的独特案例，在收到疱疹疫苗接受疱疹疫苗后呈现出严重的HV。彻底的文献综述仅产生与1997年内科纲的毒液疫苗的血管反应类似的一种类似情况;然而，已经发现了关于疱疹疫苗的其他报告的病例。我们的案例呈罕见瞥见含有Varicella疫苗给药的HV。

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