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首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Sonographic surveillance for the detection of contralateral metachronous breast cancer in an Asian population.
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Sonographic surveillance for the detection of contralateral metachronous breast cancer in an Asian population.

机译:超声检查用于检测亚洲人群对侧异时性乳腺癌。

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OBJECTIVE: This study was designed to assess the diagnostic indexes of sonographic surveillance with mammography for the detection of metachronous contralateral breast cancer. MATERIALS AND METHODS: Between January 2003 and December 2003, 1,706 breast sonographic examinations were performed by three radiologists in 1,256 Asian women with a history of surgery for breast cancer in one breast as an adjunct screening test to mammography in an academic medical center. We evaluated the biopsy recommendation rate, a diagnostic index, of the combination of whole-breast sonography and mammography for the detection of contralateral metachronous breast cancers and the positive predictive value (PPV) of this biopsy recommendation rate. RESULTS: Based on 1,706 examinations in 1,256 women, the biopsy recommendation rate was 3.5% per patient and 2.6% per examination. The PPV of the biopsy recommendation rate was 41.0% with 18 breast cancers diagnosed (cancer detection rate, 1.4% per patient and 1.1% per examination). Among these cancers, two were detected on sonography alone. One false-negative cancer was found on the next sonographic examination but could not be seen on the next mammographic examination. CONCLUSION: With a false-negative rate of only 0.06% and a PPV of 41.0% for the biopsy recommendation rate, our results suggest that annual sonography could be a useful adjunctive tool to mammography for the detection of metachronous contralateral cancers.
机译:目的:本研究旨在评估乳腺X线摄影检查对异时对侧乳腺癌的诊断指标。材料与方法:2003年1月至2003年12月,三位放射科医生对1256名有乳腺癌手术史的亚洲女性进行了1706例乳房超声检查,作为在学术医学中心进行乳房X线摄影的辅助筛查测试。我们评估了全乳超声和乳腺X线摄影相结合的活检推荐率,作为诊断对侧异时性乳腺癌的诊断指标,以及该活检推荐率的阳性预测值(PPV)。结果:根据对1,256名女性的1,706项检查,活检推荐率分别为每名患者3.5%和每项检查2.6%。活检推荐率的PPV为41.0%,诊断出18种乳腺癌(癌症检出率,每位患者1.4%,每次检查1.1%)。在这些癌症中,仅通过超声检查就发现了两种。在下一次超声检查中发现一个假阴性癌症,但在下一次乳腺检查中看不到。结论:假阴性率仅为0.06%,活检推荐率的PPV为41.0%,我们的结果表明,年度超声检查可能是乳房X线摄影的辅助手段,可用于检测异时对侧癌。

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