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首页> 外文期刊>Alexandria Journal of Agricultural Research >Effect of vitamin C, vitamin E and B-caroten as antioxidants on passive smoking hazards in rats. [Arabic]
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Effect of vitamin C, vitamin E and B-caroten as antioxidants on passive smoking hazards in rats. [Arabic]

机译:维生素C,维生素E和B-胡萝卜素作为抗氧化剂对大鼠被动吸烟危害的影响。 [阿拉伯]

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摘要

This study investigated the effect of vitamin C, Vitamin E and B-caroten as antioxidants on Reducing smoking Hazards in rats. Twenty- four healthy adult wister male rats (150-200 gm) were allocated into four groups six rats each: a control negative group, Control positive group (exposed to passive smoking) four weeks (5 days/week) 4 cigarettes/day and two groups were given antioxidants in tow doses: low dose (0.27 mg B-carotene/day, 9 mg vitamin C/day, 7.2 mg vitamin E/day) and high dose (0.54 mg-carotene/day, 18 mg vitamin C/day, 14.4 mg vitamin E/day), those doses were given together with exposure to cigarette smoke. Food weight and food efficiency ratio were reported daily. Blood was withdrawn for determination of serum cholesterol, triglyceride, LDL and HDL. It was observed that exposure to cigarette smoke resulted in significant increase in lipid profile which is reversed by administration of antioxidants, where cholesterol, triglyceride and LDL were decreased and HDL was increased. Our results suggest that antioxidants such vitamin C, vitamin E and B carotene supplemented in diet may be helpful to reduce smoking hazards in rats.
机译:这项研究调查了维生素C,维生素E和B-胡萝卜素作为抗氧化剂对减少大鼠吸烟危害的作用。将二十四只健康的成年雄性雄性大鼠(150-200 gm)分为四组,每组六只大鼠:对照组阴性组,对照组阳性(暴露于被动吸烟)4周(5天/周),每天抽4支香烟和两组分别以两剂的剂量给予抗氧化剂:低剂量(0.27 mg B-胡萝卜素/天,9 mg维生素C /天,7.2 mg维生素E /天)和高剂量(0.54 mg胡萝卜素/天,18 mg维生素C /每天(14.4毫克维生素E /天),这些剂量与接触香烟烟雾一起服用。每天报告食物重量和食物利用率。抽取血液以测定血清胆固醇,甘油三酸酯,LDL和HDL。观察到暴露于香烟烟雾导致脂质分布显着增加,这可以通过施用抗氧化剂来逆转,其中降低胆固醇,甘油三酸酯和LDL,增加HDL。我们的研究结果表明,饮食中补充维生素C,维生素E和B胡萝卜素等抗氧化剂可能有助于减少大鼠吸烟的危害。

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