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首页> 外文期刊>The International journal of oral & maxillofacial implants >Histomorphometric Analysis of Maxillary Sinus Grafts: A Pilot Study
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Histomorphometric Analysis of Maxillary Sinus Grafts: A Pilot Study

机译：上颌窦移植的组织素质分析：试验研究

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Purpose: This pilot study evaluated and compared the degree of new bone formation following maxillary sinus graft using three different bone graft materials. Materials and Methods: Patients with an edentulous posterior maxilla (unilateral or bilateral) were included in this study and underwent a two-stage procedure. Each sinus was randomly assigned one of the three graft materials: anorganic bovine bone mineral (ABBM), anorganic equine bone mineral (AEBM), or mineralized cancellous bone allograft (MCBA). Bone core samples were obtained from the lateral wall of the grafted sites at least 8 months after maxillary sinus graft. Bone quality was evaluated during bone core retrieval. The samples were histomorphometrically analyzed using Kruskal-Wallis and Dunn-Bonferroni tests at the significance level of a = .05. Results: A total of 28 sinuses (14 unilateral and 7 bilateral) from 21 subjects, with a mean age of 61.5 (range: 33 to 75) years, were included in the study. Twenty-eight bone cores (ABBM [n = 9], AEBM [n = 9], and MCBA [n = 10]) were obtained at a mean healing time of 9.1 (range: 8 to 12) months. Six maxillary sinus membrane perforations (< =5 mm) were noted and repaired during surgery (21.4%). Histomorphometric analysis of the harvested bone cores revealed statistically significant differences in the percentage of vital bone, residual bone materials, and connective tissue/marrow among the different graft materials (Kruskal-Wallis; P < .05). The percentage of vital bone in the MCBA group (32.0% ?2.4%) was significantly greater than those in the ABBM (10.9% ?.9%) and AEBM (9.1% ?.9%) groups (P < .05). The percentage of residual bone materials in the MCBA group (5.5% ?.7%) was, however, significantly less than those in the ABBM (34.3% ?2.1%) and AEBM (38.9% ?.3%) groups (P < .05). There were no significant differences in the percentage of vital bone and residual bone materials between ABBM and AEBM (P = 1.0). Newly formed bone and residual graft materials were integrated into the surrounding tissue with no sign of inflammation or foreign-body reaction. Conclusion: Within the confines of the study, MCBA has significantly greater new bone formation than ABBM and AEBM. AEBM showed comparable histomorphometric results in all parameters (percentage of vital bone, residual bone materials, and connective tissue/marrow) to ABBM.
机译：目的：该试验研究评估并比较了使用三种不同的骨接枝材料后上颌窦移植后的新骨形成程度。材料和方法：患有薄型后颌颌骨（单侧或双侧）的患者均包含在本研究中，并进行了两阶段的过程。每个窦都被随机分配了三种接枝材料中的一种：无机牛骨矿物（ABBM），无机大床骨矿物（AEBM）或矿化松质骨同种异体移植物（MCBA）。在上颌窦移植物后至少8个月从接枝位点的侧壁获得骨核样品。在骨骼核心检索期间评估骨质。使用Kruskal-Wallis和Dunn-Bonferroni测试在= 0.05的显着水平下进行样品分析。结果：共有28个鼻窦（14个单侧和7个双侧），平均年龄为61.5（范围：33至75）岁，包括在研究中。在平均愈合时间为9.1（范围：8至12）个月，获得二十八个骨核（ABBM [n = 9]，AEBM [n = 9]和MCBA [n = 10]）。注意到六个上颌窦膜穿孔（<= 5mm）并在手术期间修复（21.4％）。收获的骨核的组织形态分析揭示了不同移植物材料中生命骨，残留骨材料和结缔组织/骨髓百分比的统计学显着差异（Kruskal-Wallis; P <.05）。 MCBA组的重要骨骼的百分比（32.0％？2.4％）明显大于ABBM（10.9％〜9％）和Aebm（9.1％Δ9％）组（P <.05）。然而，MCBA组中残留骨材料（5.5％Δ7％）的百分比显着低于ABBM（34.3％？2.1％）和Aebm（38.9％？.3％）组（P < .05）。 ABBM和AEBM之间的重要骨和残留骨材料的百分比没有显着差异（P = 1.0）。新成形的骨和残留的移植物含有没有炎症或异物反应的周围组织。结论：在该研究的范围内，MCBA具有比ABBM和AEBM更大的新骨形成。 AEBM显示了与ABBM的所有参数（重要骨，残留骨骼材料和结缔组织/骨髓）的所有参数（百分比百分比）相当的组织形态形状。

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