首页> 外文期刊>The International journal of pharmacy practice >Anticoagulation management by community pharmacists in N N ew Z Z ealand: an evaluation of a collaborative model in primary care
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Anticoagulation management by community pharmacists in N N ew Z Z ealand: an evaluation of a collaborative model in primary care

机译:N N EW Z Z Z Z Z Z Z Z Z Z Z Z Z Z的抗凝管理:评估初级保健中的协作模型

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Abstract Objectives Despite the introduction of new oral anticoagulants, vitamin K antagonists remain the mainstay of the prevention and treatment of thromboembolism. The advent of affordable point‐of‐care testing presents an opportunity for community pharmacists to provide anticoagulation management services, better utilizing their training, reducing the workload on medical practices and improving accessibility and convenience for patients. This study aimed to determine the effectiveness of anticoagulation management by community pharmacists. Methods All patients enrolled in a pilot programme for a community pharmacy anticoagulation management service using point‐of‐care international normalized ratio testing and computer‐assisted dose adjustment were included in a follow‐up study, including before–after comparison. Outcomes included time in therapeutic range ( TTR ), time above and below range, number and proportion of results outside efficacy and safety thresholds, and a comparison of care led by pharmacists and care led by a primary‐care general practitioner (GP). Key findings A total of 693 patients were enrolled, predominantly males over 65 years of age with atrial fibrillation. The mean TTR was 78.6% (95% CI 49.3% to 100%). A subgroup analysis ( n ?=?221) showed an increase in mean TTR from 61.8% under GP ‐led care to 78.5% under pharmacist‐led care ( P ??0.001), reflecting a reduction in the time above and, in particular, below the range. The mean TTR by pharmacy ranged from 71.4% to 84.1%. The median number of tests per month was not statistically different between GP ‐ and pharmacist‐led care. Conclusions Community‐pharmacist‐led anticoagulation care utilizing point‐of‐care testing and computerized decision support is safe and effective, resulting in significant improvements in TTR . Our results support wider adoption of this model of collaborative care.
机译:摘要目的尽管新的口腔抗凝血剂引入,维生素K拮抗剂仍然是预防和治疗血栓栓塞的主要支柱。经济实惠的护理人员测试的出现为社区药剂师提供了一个抗凝管理服务,更好地利用他们的培训,减少了对医疗实践的工作量以及改善患者的可行性和便利性的机会。本研究旨在确定社区药剂师抗凝管理的有效性。方法使用护理点国际规范化比率检测和计算机辅助剂量调整,所有患者纳入社区药房抗凝管理服务的试点计划的所有患者都包含在后续研究中,包括在比较之前。结果包括治疗范围(TTR)的时间,高于和低于范围,结果的疗效和安全阈值的结果,数量和比例,以及由初级保健一般从业者(GP)的药剂师和护理的护理比较。主要发现共征收693名患者,主要是65岁以上的患者具有心房颤动。平均TTR为78.6%(95%CI 49.3%至100%)。亚组分析(n?=Δ221)显示在药剂师LED护理下GP-LED护理下的61.8%的平均值增加到78.5%(p≤≤0.001),反映了上述时间和,特别是,在范围之下。药房的平均值范围从71.4%到84.1%。 GP和药剂师LED护理之间的每月中位数的每月的中位数并不统计学。结论使用护理点测试和计算机化决策支持的社区药剂师LED抗凝护理是安全有效的,导致TTR的显着改进。我们的结果支持更广泛地采用这种协作护理。

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