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首页> 外文期刊>Head and neck: Journal for the sciences and specialities of the head and neck >A critical analysis of the prognostic performance of the 8th edition American Joint Committee on Cancer staging for metastatic cutaneous squamous cell carcinoma of the head and neck
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A critical analysis of the prognostic performance of the 8th edition American Joint Committee on Cancer staging for metastatic cutaneous squamous cell carcinoma of the head and neck

机译：第8版美国联合癌症癌症癌症癌癌癌癌癌前瞻性癌症的批判性分析

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Background The 8th edition AJCC staging of cutaneous squamous cell carcinoma of the head and neck (cSCCHN) incorporated extranodal extension (ENE) for the first time. This study compared the prognostic performance of the 7th and 8th edition staging for cSCCHN with nodal metastases. Methods Retrospective analysis of 96 patients with metastatic cSCCHN, comparing the ability of staging systems to predict disease-specific and overall survival (OS) using the proportion of variation explained and Harrell's C-index. Results In AJCC8, the N classification was upstaged in 77% of patients due to the presence of ENE and 88% of patients were classified as TNM stage IV. AJCC8 was inferior to AJCC7 in predicting disease-specific survival for both N and TNM stages, and OS by TNM stage. Conclusions The majority of patients with metastatic cSCCHN have ENE and are classified as TNM stage IV based on the 8th edition staging, resulting in poor prognostic performance.
机译：背景技术第8版AJCC鳞状细胞癌的头部和颈部（CSCCHN）首次加入了外延延伸部（ENE）。 本研究比较了CSCCHN与节点转移的第7和第8版分期的预后性能。 方法采用五分期系统术治疗术治疗疾病特异性和整体存活（OS）哈尔的C折射，比较分期系统患者的回顾性分析。 结果在AJCC8中，由于eNE存在，77％的患者升高了N分类，并且88％的患者被归类为TNM阶段IV。 AJCC8差于预测N和TNM阶段的疾病特异性存活率，以及TNM阶段的OS。 结论基于第8版分期，大多数转移性CSCCHN患者的转移性CSCCHN患者归类为TNM阶段IV，导致预后性能差。

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