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首页> 外文期刊>AJNR. American journal of neuroradiology >Sixty-four-section CT cerebral perfusion evaluation in patients with carotid artery stenosis before and after stenting with a cerebral protection device.
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Sixty-four-section CT cerebral perfusion evaluation in patients with carotid artery stenosis before and after stenting with a cerebral protection device.

机译：颈动脉狭窄患者支架置入前后用脑保护装置进行的六十四节CT脑灌注评估。

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摘要

BACKGROUND AND PURPOSE: Brain tissue viability depends on cerebral blood flow (CBF) that has to be kept within a narrow range to avoid the risk of developing ischemia. The aim of the study was to evaluate by 64-section CT (VCT) the cerebral perfusion modifications in patients with severe carotid stenosis before and after undergoing carotid artery stent placement (CAS) with a cerebral protection system. MATERIALS AND METHODS: Fifteen patients with unilateral internal carotid stenosis (>or=70%) underwent brain perfusional VCT (PVCT) 5 days before and 1 week after the stent-placement procedure. CBF and mean transit time (MTT) values were measured. RESULTS: Decreased CBF and increased MTT values were observed in the cerebral areas supplied by the stenotic artery as compared with the areas supplied by the contralateral patent artery (P < .001). A significant normalization of the perfusion parameters was observed after the stent-placement procedure (mean pretreatment MTT value, 5.3 +/- 0.2; mean posttreatment MTT value, 4.3 +/- 0.18, P < .001; mean pretreatment CBF value, 41.2 mL/s +/- 2.1; mean posttreatment CBF value, 47.9 mL/s +/- 2.9, P < .001). CONCLUSIONS: PVCT is a useful technique for the assessment of the hemodynamic modifications in patients with severe carotid stenosis. The quantitative evaluation of cerebral perfusion makes it a reliable tool for the follow-up of patients who undergo CAS.
机译：背景与目的：脑组织生存能力取决于脑血流（CBF），必须将其保持在狭窄范围内，以避免发生缺血的风险。这项研究的目的是通过64断层CT（VCT）评估带有脑保护系统的颈动脉支架置入术（CAS）前后严重颈动脉狭窄患者的脑灌注改变。材料与方法：15例单侧颈内动脉狭窄（> == 70％）的患者在支架置入术前5天和1周后接受了脑灌注VCT（PVCT）。测量了CBF和平均通过时间（MTT）值。结果：与对侧上动脉的供血面积相比，狭窄动脉供血的大脑区域CBF降低，MTT值升高（P <.001）。支架置入过程后观察到灌注参数的显着标准化（平均MTT预处理值5.3 +/- 0.2; MTT平均值4.3 +/- 0.18，P <.001; CBF平均值41.2 mL / s +/- 2.1;平均治疗后CBF值，47.9 mL / s +/- 2.9，P <.001）。结论：PVCT是评估严重颈动脉狭窄患者血流动力学改变的有用技术。对脑灌注的定量评估使其成为随访接受CAS患者的可靠工具。

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