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Preoperative staging of papillary thyroid carcinoma: comparison of ultrasound imaging and CT.

机译:甲状腺乳头状癌的术前分期:超声成像与CT的比较。

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OBJECTIVE: The purpose of this study was to compare the diagnostic accuracy of ultrasound imaging with that of CT in the preoperative evaluation of primary tumors and cervical lymph nodes in patients with papillary thyroid carcinoma and to determine whether CT has greater diagnostic value than ultrasound alone in the care of these patients. MATERIALS AND METHODS: The study population consisted of 299 consecutively registered patients with pathologically proven papillary thyroid carcinoma. The diagnostic accuracies of ultrasound, CT, and the combination of ultrasound and CT in the evaluation of primary tumors and lymph node metastasis were compared. We performed subgroup analysis to compare the findings on papillary thyroid microcarcinoma (10 mm in maximum diameter or smaller) with the findings on papillary thyroid carcinoma larger than 1 cm in maximum diameter. RESULTS: Ultrasound was more accurate than CT in prediction of the presence of extrathyroidal tumor extension and of malignant disease in both thyroid lobes (p < 0.05) for overall lesions and for the two subgroups. In prediction of central node (neck level VI) metastasis, CT had greater sensitivity than ultrasound alone (p = 0.04) for overall lesions. Although the combination of ultrasound and CT had greater sensitivity than ultrasound alone in prediction of the presence of central node metastasis in the two subgroups, the sensitivity of the combination of ultrasound and CT did not reach statistical significance for papillary thyroid microcarcinoma. Ultrasound alone and ultrasound with CT had greater sensitivity than CT in prediction of lateral node (levels II-V) metastasis, but there was no significant difference in diagnostic value between ultrasound and the combination of ultrasound and CT for overall lesions or for the two subgroups (p > 0.05). CONCLUSION: High-resolution ultrasound can be accurate in preoperative evaluation for extrathyroidal tumor extension and lateral lymph node metastasis. CT had greater sensitivity than ultrasound alone in the detection of central lymph node metastasis for all lesions. For papillary thyroid microcarcinoma, however, there was no significant difference in the diagnostic accuracy rates of ultrasound, CT, and the combination of ultrasound and CT.
机译:目的:本研究的目的是比较超声成像与CT在甲状腺乳头状癌患者术前评估原发性肿瘤和宫颈淋巴结的诊断准确性方面,并确定CT是否比单纯超声诊断具有更大的诊断价值。这些病人的护理。材料与方法:研究人群包括299例经病理证实的甲状腺乳头状癌的连续登记患者。比较了超声,CT的诊断准确性,以及超声和CT结合在评估原发肿瘤和淋巴结转移方面的准确性。我们进行了亚组分析,以比较甲状腺乳头状癌(最大直径为10毫米或更小)的发现与最大直径大于1厘米的甲状腺乳头状癌的发现。结果:超声在预测整个病变和两个亚组的两个甲状腺叶中存在甲状腺外肿瘤扩展和恶性疾病方面均比CT准确(p <0.05)。在预测中心淋巴结转移(颈部VI级)时,CT对整体病变的敏感性高于仅超声检查(p = 0.04)。尽管超声和CT组合在预测两个亚组中存在中心结转移方面比单独使用超声具有更高的敏感性,但是超声和CT组合对乳头状甲状腺微癌的敏感性没有统计学意义。超声和CT联合超声在预测侧结(II-V级)转移方面的敏感性比CT高,但是超声和超声与CT联合检查对总病变或两个亚组的诊断价值无显着差异(p> 0.05)。结论:高分辨率超声可以准确评估术前甲状腺外肿瘤的扩散和外侧淋巴结转移。在所有病变的中央淋巴结转移的检测中,CT的敏感性均高于超声检查。但是,对于甲状腺乳头状微癌,超声,CT以及超声与CT的组合的诊断准确率没有显着差异。

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