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首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Optimal acquisition delay for dynamic contrast-enhanced MRI of hypervascular hepatocellular carcinoma.
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Optimal acquisition delay for dynamic contrast-enhanced MRI of hypervascular hepatocellular carcinoma.

机译：动态对比增强MRI对高血管性肝细胞癌的最佳采集延迟。

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OBJECTIVE: The purpose of this study was to prospectively determine the optimal acquisition delay for imaging of hypervascular hepatocellular carcinoma with multiphasic dynamic contrast-enhanced MRI. SUBJECTS AND METHODS: One hundred twenty patients with chronic hepatic disease underwent three-phase dynamic contrast-enhanced MRI of the liver, which revealed 49 hypervascular hepatocellular carcinomas. Abdominal aortic contrast arrival time was determined with test bolus imaging. Patients were assigned to one of the following four groups according to acquisition delay determined from abdominal aortic contrast arrival time to the middle of the k-space for the early, late hepatic arterial, and portal venous phases: 0, 12, and 49 seconds (group 1); 3, 15, and 52 seconds (group 2); 6, 18, and 55 seconds (group 3); and 9, 21, and 58 seconds (group 4). Each phase of imaging took 12 seconds. Contrast enhancement in the abdominal aorta, portal vein, hepatic parenchyma, and hepatocellular carcinoma was evaluated. Peritumoral sinusoidal enhancement (i.e., coronal enhancement) also was assessed. RESULTS: Intense enhancement of hepatocellular carcinoma with little background parenchymal enhancement occurred at 9-12 seconds (p < 0.05) after arrival of contrast material in the abdominal aorta. Hepatocellular carcinoma-to-liver contrast began to decline at 15 seconds and decreased to less than zero at 49 seconds. The conspicuity of coronal enhancement was greater 21 seconds after contrast administration than in earlier phases. CONCLUSION: With the injection protocol used in this study, optimal acquisition delay-determined from abdominal aortic contrast arrival time to the middle of the k-space acquisition-for imaging of hypervascular hepatocellular carcinoma was 9-12, 21 or more, and 49 seconds for the early, late hepatic arterial, and portal venous phases.
机译：目的：本研究旨在前瞻性地确定多相动态对比增强MRI对高血管性肝细胞癌成像的最佳采集延迟。研究对象和方法：对120例慢性肝病患者进行了三相动态肝脏增强MRI检查，显示49例高血管性肝细胞癌。腹主动脉造影到达时间用推注成像确定。根据从腹主动脉造影到达时间到早期，晚期肝动脉和门静脉阶段的k空间中间所确定的采集延迟，将患者分为以下四组之一：0、12和49秒（第1组）; 3、15和52秒（第2组）; 6、18和55秒（第3组）;和9、21和58秒（第4组）。成像的每个阶段花费12秒。评估了腹主动脉，门静脉，肝实质和肝细胞癌的对比增强。还评估了腹膜窦正弦增强（即冠状增强）。结果：造影剂到达腹主动脉后9-12秒（p <0.05），肝细胞癌发生了强烈的增强，而实质实质却很少。肝细胞肝-肝对比度在15秒时开始下降，在49秒时下降至小于零。对比剂给药后21秒，冠状动脉增强的显着性高于早期。结论：使用本研究中的注射方案，从腹主动脉造影剂到达时间到k空间采集中间的最佳采集延迟（用于血管性肝细胞癌的成像）为9-12、21或更多和49秒用于早期，晚期肝动脉和门静脉期。

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