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首页> 外文期刊>Human vaccines & immunotherapeutics. >The first report evaluating the post-exposure rabies prophylaxis in children exposed to animals in the Lublin Province (Eastern Poland) in 2010-2016-a retrospective study
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The first report evaluating the post-exposure rabies prophylaxis in children exposed to animals in the Lublin Province (Eastern Poland) in 2010-2016-a retrospective study

机译：2010 - 2016年 - 2016年 - 2016-2016--2016-- 2010 - 2016-2016-- 2010-2016--2016-评估了暴露于卢布林省（东波兰东部）的儿童的暴露后狂犬病预防的狂犬病的预防

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Introduction: Rabies continues to be one of the most important viral diseases and remains a significant threat to public health across the globe. The World Health Organization (WHO) has determined that most rabies cases occur in children. Dog bites on humans are a major public-health problem. Poland has not achieved rabies free status yet. Post-exposure prophylaxis (PEP) in humans can effectively prevent death after exposure to a potentially infected animal. The aim: The main objective of this study was to estimate the frequency of PEP among children exposed to animals, who had attended consultations at the Department of Infectious Diseases for Children in the Jan Bo(z) over doty Hospital in Lublin. Patients and methods: We retrospectively analyzed the medical records from the period of 2010-2016 of all pediatric patients (0-17 years of age) who had been exposed to animals and attended consultations at the Department of Infectious Diseases for Children in the Jan Bo(z) over doty Hospital in Lublin. Results: During the studied period, 519 children who had been exposed to animals attended consultations, and a prophylactic procedure consisting of active immunization was applied to 32.8%. The male children accounted for 55.3%. The mean age was 9.2 years. The biggest group of children (406) had been exposed to dogs, 62 children to cats, and 15 to rats. Most children had upper-limbs injuries. During the studied period, i.e. 2010-2016, there were 1713 confirmed cases of rabid animals in Poland, and 60 cases were recorded in the Lublin Province. We did not observe any cases of rabies in our exposed and vaccinated patients. Conclusions: The number of rabid animals in the Lublin Province had decreased to low levels, but the expected decrease in the number of PEP's administered did not occur. Since all children were vaccinated in accordance with the recommendations, the possible reason for vaccination's being administered in the quantities greater than the number of rabid animals recorded in the Lublin Province are bites by animals unavailable for veterinary observations and also the lack of more frequent reports regarding the current epizootic situation of rabies. The use of rabies immunoglobulin (RIG) in children in the Lublin Province is at a very low level, i.e. at 0.58%. The yearly numbers of exposed pediatric patients were at similar levels, which indicates that education programs should be introduce to reduce the number of animal bites in children.
机译：简介：狂犬病仍然是最重要的病毒疾病之一，仍然是全球公共卫生的重要威胁。世界卫生组织（世卫组织）确定大多数狂犬病病例发生在儿童中。人类的狗是一个主要的公共卫生问题。波兰尚未获得狂犬病的自由状态。暴露后的预防（PEP）在暴露于潜在感染的动物后可以有效地防止死亡。目的：本研究的主要目标是估计暴露于动物的儿童的PEP的频率，他们在卢布林的Doty医院在Jan Bo（Z）的儿童系中发表咨询。患者和方法：我们回顾性地分析了2010-2016的医疗记录，所有儿科患者（0-17岁）已接触到动物，并在Jan Bo的儿童传染病部参阅磋商（z）卢布林的Doty医院。结果：在研究期间，519名接触动物的儿童参加咨询，并将具有主动免疫的预防程序应用于32.8％。男性儿童占55.3％。平均年龄为9.2岁。最大的一群儿童（406）已接触到狗，62名儿童到猫，15岁。大多数孩子都有肢体伤害。在研究期间，即2010-2016，波兰的狂欢动物有1713例确诊病例，卢布林省60例。我们没有观察我们暴露和疫苗的患者中的任何狂犬病病例。结论：卢布林省的rabid动物数量下降到低水平，但未发生百分之百举行的预期减少。由于所有儿童都按照建议进行接种疫苗，因此疫苗接种的可能性在卢布林省中记载的狂犬病动物数量的数量施用，因兽医观察而无法使用的动物咬伤，并且还缺乏更多频繁的报告狂犬病的目前的癫痫态势。狂犬病免疫球蛋白（钻机）在卢布林省的儿童中的使用非常低，即0.58％。暴露的儿科患者的年数在类似的水平，这表明应该介绍教育计划，以减少儿童的动物叮咬数量。

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