Iron and liver cancer.

Deugnier Y

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Iron and liver cancer.

机译：铁和肝癌。

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Mechanisms whereby iron may act in carcinogenesis are induction of oxidative stress, facilitation of tumor growth, and modification of the immune system. Results of clinical and epidemiologic studies demonstrate a strong association between iron excess (even at mild levels) and the development of cancer at any site, but they do not indicate whether this reflects a causal link or an indirect association through other factors (i.e., aging, alcohol consumption, and insulin resistance). Findings obtained from experimental work are not conclusive with respect to a direct carcinogenic role of iron, but they support a carcinogenic or co-carcinogenic role of iron in chemically induced carcinogenesis.

机译：铁可能在致癌作用中发挥作用的机制是诱导氧化应激，促进肿瘤生长和改变免疫系统。临床和流行病学研究的结果表明，铁过量（即使在轻度水平）与任何部位的癌症发展之间都有很强的联系，但没有说明这是否反映了因果关系或其他因素（例如衰老）的间接联系。，酒精消耗和胰岛素抵抗）。从实验工作中获得的发现对于铁的直接致癌作用尚无定论，但它们支持铁在化学诱导的致癌作用中的致癌作用或共致癌作用。

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《Alcohol》 |2003年第2期|共6页
作者
Deugnier Y;
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正文语种 eng
中图分类预防医学、卫生学;内科学;
关键词
Iron; Relationship by association; carcinogenesis; Liver Cancer; Iron measurement; 铁;

机译：铁;缔合关系;致癌作用;肝癌;铁测定;铁;

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专利

1. Multifunctional doxorubicin loaded superparamagnetic iron oxide nanoparticles for chemotherapy and magnetic resonance imaging in liver cancer. [J] . Maeng JH, Lee DH, Jung KH, Biomaterials . 2010,第18期

机译：载有多功能阿霉素的超顺磁性氧化铁纳米粒子，用于肝癌的化学疗法和磁共振成像。
2. Relationship between transferrin-iron saturation, alcohol consumption, and the incidence of cirrhosis and liver cancer. [J] . Ioannou GN, Weiss NS, Kowdley KV Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association . 2007,第5期

机译：转铁蛋白铁饱和度，饮酒量与肝硬化和肝癌发生率之间的关系。
3. Iron and liver cancer. [J] . Deugnier Y Alcohol . 2003,第2期

机译：铁和肝癌。
4. Preparation and evaluation of human serum albumin-methotrexate nanoparticles as a potential drug delivery system for cancer. [C] . Azade Taheri, Rassul Dinarvand, Fateme Atyabi, Annual meeting exposition of the Controlled Release Society . 2010

机译：人血清白蛋白-甲氨蝶呤纳米颗粒的制备和评估，作为癌症的潜在药物递送系统。
5. The role of PGE2 biosynthesis and metabolism in liver injury and liver cancer. [D] . Yao, Lu. 2015

机译：PGE2生物合成和代谢在肝损伤和肝癌中的作用。
6. Iron overload correlates with serum liver fibrotic markers and liver dysfunction: Potential new methods to predict iron overload-related liver fibrosis in thalassemia patients [O] . Man Wang, Rongrong Liu, Yuzhen Liang, 2017

机译：铁超载与血清肝纤维化指标和肝功能障碍相关：预测地中海贫血患者铁超载相关肝纤维化的潜在新方法
7. Study on the Clinical Significance of Superparamagnetic Iron Oxide-Enhanced MRI for Diagnosis of Liver Metastasis from Colorectal Cancer. [O] . M. Yano, M. Itabashi, S. Kameoka 2001

机译：超顺磁性氧化铁增强MRI临床意义研究结直肠癌肝转移诊断的研究。

Iron and liver cancer.

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