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首页> 外文期刊>Zoonoses and Public Health >West Nile virus infection in horses in Saudi Arabia (in 2013-2015)
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West Nile virus infection in horses in Saudi Arabia (in 2013-2015)

机译：西尼罗河病毒感染在沙特阿拉伯的马（2013-2015）

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摘要

West Nile virus (WNV) is an important emerging zoonotic arbovirus giving rise to clinical syndromes of varying severity in humans and horses. Culex mosquitoes are the main vector. Although WNV has been reported in many countries in the Middle East and Asia, little is known about its prevalence in equine populations in the Arabian Peninsula. We have carried out a serological study on 200 horses to assess WNV infection in the Eastern and Central regions of Saudi Arabia in 2013-2015. Sera were tested for the presence of WNV antibodies in parallel using a commercial enzyme-linked immunosorbent assay (ELISA) kit and microneutralization (MN) tests. In comparison with the MN assay used as "gold standard," we find the ELISA had a sensitivity of 94.7% and specificity of 80.1%. The prevalence of WNV neutralizing antibody ranged from 5 (17.3%) of 29 sera collected in Riyadh up to 15 (55.6%) of 27 sera collected from Al-Qateef. These findings highlight the need to be aware of the possibility of WNV disease in humans and horses presenting with central nervous system disease in the Kingdom of Saudi Arabia.
机译：西尼罗河病毒（WNV）是一种重要的新兴的芽孢杆菌，其产生了不同严重程度的人类和马匹的临床综合症。 Culex蚊子是主要的载体。虽然WNV在中东和亚洲的许多国家报道，但对阿拉伯半岛的马群人的普遍众所周知，虽然众所周知。我们对2003 - 2015年沙特阿拉伯东部和中部地区评估了200匹马的血清学研究。使用商业酶联免疫吸附测定（ELISA）试剂盒和微生力和测量试验，对血清进行WNV抗体的存在。与用作“黄金标准”的Mn测定相比，我们发现ELISA的敏感性为94.7％，特异性为80.1％。 WNV中和抗体的患病率范围为5（17.3％）的29血清，从Al-Q atef中收集的27个血清收集的15（55.6％）。这些发现突出了在沙特阿拉伯王国在中枢神经系统疾病中介绍了人类和马匹中WNV病的可能性。

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