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首页> 外文期刊>Depression and anxiety >Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2-week ambulatory assessment study
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Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2-week ambulatory assessment study

机译：睡眠，昼夜节律和抑郁症和焦虑症的身体活动模式：2周的行动评估研究

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摘要

Background Actigraphy may provide a more valid assessment of sleep, circadian rhythm (CR), and physical activity (PA) than self-reported questionnaires, but has not been used widely to study the association with depression/anxiety and their clinical characteristics. Methods Fourteen-day actigraphy data of 359 participants with current (n = 93), remitted (n = 176), or no (n = 90) composite international diagnostic interview depression/anxiety diagnoses were obtained from the Netherlands Study of Depression and Anxiety. Objective estimates included sleep duration (SD), sleep efficiency, relative amplitude (RA) between day-time and night-time activity, mid sleep on free days (MSF), gross motor activity (GMA), and moderate-to-vigorous PA (MVPA). Self-reported measures included insomnia rating scale, SD, MSF, metabolic equivalent total, and MVPA. Results Compared to controls, individuals with current depression/anxiety had a significantly different objective, but not self-reported, PA and CR: lower GMA (23.83 vs. 27.4 milli-gravity/day, p = .022), lower MVPA (35.32 vs. 47.64 min/day, p = .023), lower RA (0.82 vs. 0.83, p = .033). In contrast, self-reported, but not objective, sleep differed between people with current depression/anxiety compared to those without current disorders; people with current depression/anxiety reported both shorter and longer SD and more insomnia. More depressive/anxiety symptoms and number of depressive/anxiety diagnoses were associated with larger disturbances of the actigraphy measures. Conclusion Actigraphy provides ecologically valid information on sleep, CR, and PA that enhances data from self-reported questionnaires. As those with more severe or comorbid forms showed the lowest PA and most CR disruptions, the potential for adjunctive behavioral and chronotherapy interventions should be explored, as well as the potential of actigraphy to monitor treatment response to such interventions.
机译：背景技术可以提供比自述问卷的睡眠，昼夜节律（CR）和身体活动（PA）提供更有效的评估，但尚未广泛用于研究与抑郁/焦虑和临床特征的关联。方法从荷兰抑郁和焦虑的研究中获得了359名具有当前（n = 93）的359名参与者（n = 93）的参与者（n = 93）的参与者（n = 93），或者no（n = 90）综合诊断。客观估计包括睡眠持续时间（SD），睡眠效率，日间和夜间活动之间的相对幅度（RA），在空闲天（MSF），总机动活动（GMA），以及中等剧烈的PA之间（MVPA）。自我报告的措施包括失眠率，SD，MSF，代谢等效物和MVPA。结果与对照相比，具有目前抑郁/焦虑的个体具有明显不同的目标，但不报告，PA和Cr：下GMA（23.83与27.4毫级 - 重力/天，P = .022），下部MVPA（35.32与47.64分钟/天，p = .023），下拉（0.82 vs.0.83，p = .033）。相比之下，自我报告，但没有客观，与当前抑郁症/焦虑的人之间的睡眠不同，与那些没有当前疾病的人;具有目前抑郁症/焦虑的人报告较短和更长的SD和更多的失眠。更抑制/焦虑症状和抑郁/焦虑诊断的数量与戏剧措施的较大扰动有关。结论Actigraphy提供有关睡眠，CR和PA的生态有效信息，可增强自报告问卷的数据。由于具有更严重或可康的形式的那些表现出最低的PA和大多数CR破坏，因此应探索辅助行为和计时干预的潜力，以及戏法监测对此类干预措施的治疗响应的潜力。

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