Treatment of Actinic Keratoses: A Randomized Split-Site Approach Comparison of Sequential 5-Fluorouracil and 5-Aminolevulinic Acid Photodynamic Therapy to 5-Aminolevulinic Acid Photodynamic Monotherapy

Pei Susan; Kaminska Edidiong C. N.; Tsoukas Maria M.

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Treatment of Actinic Keratoses: A Randomized Split-Site Approach Comparison of Sequential 5-Fluorouracil and 5-Aminolevulinic Acid Photodynamic Therapy to 5-Aminolevulinic Acid Photodynamic Monotherapy

机译：活体角膜的治疗：序贯5-氟尿嘧啶和5-氨基乙酸光动力治疗对5-氨基纤维酸光动力学单疗法的随机分裂部位比较

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BACKGROUND Actinic keratoses (AKs) are skin lesions resulting from sun exposure and carry a risk of developing into squamous cell carcinoma. Current therapies for AK eradication include topical 5-fluorouracil (5-FU) and photodynamic therapy (PDT) with topical 5-aminolevulinic acid ( ALA). However, sequential therapy with 5-FU-ALA-PDT may offer improved outcome compared to ALA-PDT alone.

机译：背景光碱角膜（AKS）是由于阳光暴露产生的皮肤病变，并携带鳞状细胞癌的风险。 AK删除的当前疗法包括局部5-氟尿嘧啶（5-FU）和光动力治疗（PDT），具有局部5-氨基乙酰丙酸（ALA）。然而，与5-FU-ALA-PDT的顺序治疗可以单独与ALA-PDT相比提供改善的结果。

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《Dermatologic surgery》 |2017年第9期|共6页
作者
Pei Susan; Kaminska Edidiong C. N.; Tsoukas Maria M.;
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Univ Wisconsin Dept Dermatol Madison WI USA;

Univ Chicago NorthShore Univ Hlth Syst Sect Dermatol Pritzker Sch Med Skokie IL USA;

Univ Illinois Dept Dermatol 1801 W Taylor St Suite 3E Chicago IL 60612 USA;

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正文语种 eng
中图分类皮肤病学与性病学;
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1. Treatment of Actinic Keratoses: A Randomized Split-Site Approach Comparison of Sequential 5-Fluorouracil and 5-Aminolevulinic Acid Photodynamic Therapy to 5-Aminolevulinic Acid Photodynamic Monotherapy [J] . Pei Susan, Kaminska Edidiong C. N., Tsoukas Maria M. Dermatologic surgery . 2017,第9期

机译：活体角膜的治疗：序贯5-氟尿嘧啶和5-氨基乙酸光动力治疗对5-氨基纤维酸光动力学单疗法的随机分裂部位比较
2. Topical photodynamic therapy of actinic keratoses with 5-aminolevulinic acid: Randomized controlled trial with six months follow-up [J] . Buinauskaite E., Maciulaitis R., Buinauskiene J., The Journal of dermatological treatment . 2014,第6期

机译：5-氨基乙酰丙酸对光化性角化病的局部光动力治疗：六个月随访的随机对照试验
3. Pain during topical photodynamic therapy of actinic keratoses with 5-aminolevulinic acid and red light source: randomized controlled trial. [J] . Evelina Buinauskaite, Rimantas Zalinkevicius, Jurate Buinauskiene, Photodermatology, photoimmunology and photomedicine . 2013,第4期

机译：用5-氨基乙酰丙酸和红光源对光化性角蛋白进行局部光动力治疗时的疼痛：随机对照试验。
4. Topical photodynamic therapy with 5-aminolevulinic acid in the treatment of actinic keratoses: a first clinical study [C] . Sigrid Karrer, Univ. Regensburg, Regensburg, Photochemotherapy: Photodynamic Therapy and Other Modalities . 1996

机译：5-氨基乙酰丙酸局部光动力疗法治疗光化性角化病的首次临床研究
5. The effect of 5-aminolevulinic acid based photodynamic therapy and photochemical internalization of bleomycin on the F98 rat glioma cell line. [D] . Kharkhuu, Khishigzaya. 2008

机译：基于5-氨基乙酰丙酸的光动力疗法和博来霉素的光化学内在化对F98大鼠神经胶质瘤细胞系的影响。
6. Tolerability of Photodynamic Therapy Using 10 5-Aminolevulinic Acid Hydrochloride Gel for Treating Actinic Keratoses on Surface Areas Larger than 75cm [O] . Angela Yen Moore, Stephen Moore 2020

机译：使用10％5-氨基乙酰丙烯酸盐酸盐凝胶的光动力治疗可耐受性用于在大于75厘米的表面积上处理光化角膜
7. A randomized clinical trial of photodynamic therapy with methylaminolevulinate versus 3 diclofenac plus hyaluronic acid gel for the treatment of multiple actinic keratoses of the face and scalp. [O] . Zane C, Facchinetti E, Rossi M, 2014

机译：用甲基氨基乙酰丙酸酯与3％双氯芬酸加透明质酸凝胶进行光动力疗法的光动力疗法的随机临床试验，用于治疗面部和头皮的多种光化性角化病。

Treatment of Actinic Keratoses: A Randomized Split-Site Approach Comparison of Sequential 5-Fluorouracil and 5-Aminolevulinic Acid Photodynamic Therapy to 5-Aminolevulinic Acid Photodynamic Monotherapy

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