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首页> 外文期刊>Dermatologic surgery >Systematic Review of Surgical Treatment and Outcomes After Local Surgery of Primary Cutaneous Melanomas of the Penis and Scrotum.
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Systematic Review of Surgical Treatment and Outcomes After Local Surgery of Primary Cutaneous Melanomas of the Penis and Scrotum.

机译:阴茎和阴囊局部皮肤黑瘤局部手术后手术治疗和结果的系统审查。

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摘要

Few data exist to guide surgical management and counseling about local recurrence after surgery of primary male genital melanoma. To compile all available data on local recurrence rates after surgery of primary cutaneous melanoma of the penis and scrotum. A systematic review of PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Excerpta Medica database (EMBASE), and Web of Science identified all surgically treated penile and scrotal melanomas that reported local recurrence status and follow-up time. One hundred twenty-seven melanomas from 74 manuscripts were included. Eighty-six percent of melanomas were located on the penis, and 14% were located on the scrotum. Average follow-up time was 35.7 months. Scrotal melanomas were predominantly treated with organ-sparing surgeries (16/18, 88.9%), whereas penile melanomas were treated more often with amputation (61/109, 56.0%). Overall, local recurrence rate was 15.7% (20/127). Local recurrence rates for penile cases were 18.8% (9/48) after organ-sparing surgery versus 13.1% (8/61) for amputative surgery. Local recurrence rates were 66.7% (4/6) after positive surgical margins versus 10.2% (5/49) after negative surgical margins. Local recurrence rates are high after both organ-sparing and amputative surgery of primary cutaneous melanoma of the penis and scrotum. There is a need to standardize reporting for this rare tumor, as more complete data are necessary to develop consensus guidelines for surgical management of male genital melanoma.
机译:存在很少的数据,以指导手术管理和咨询初级男性生殖器马伦马拉肿瘤手术后局部复发。在阴茎和阴囊的主要皮肤黑素瘤手术后编译局部复发率的所有可用数据。对PubMed,Literatura Latino-Americana e Do Caribe EmCiênciasdasaúde(Lilacs),Excerpta Medica数据库(EMBASE)以及科学网鉴鉴定了所有手术治疗的阴茎和阴囊黑色素,报告了当地复发状态和随访时间。包括来自74个手稿的一百二十七个黑素瘤。百分之八十六个黑素瘤位于阴茎上,14%位于阴囊上。平均随访时间为35.7个月。阴囊黑素瘤主要用器官制剂手术治疗(16/18,88.9%),而截肢(61/109,56.0%)更常用过阴茎黑色素瘤。总体而言,地方复发率为15.7%(20/127)。在器官备件手术与截肢手术中的13.1%(8/61)后,阴茎病例的局部复发率为18.8%(9/48)。阳性手术边距在阴性外科余量后的10.2%(5/49),局部复发率为66.7%(4/6)。在阴茎和阴囊的主要皮肤黑素瘤的器官备件和截肢手术后,局部复发率很高。有必要标准化这种罕见肿瘤的报告,因为更完整的数据是制定与男性生殖器瘤外科手术管理的共识指导。

著录项

  • 来源
    《Dermatologic surgery》 |2018年第9期|共11页
  • 作者单位

    Indiana University School of Medicine Indianapolis Indiana;

    Duke University School of Medicine Durham North Carolina;

    Department of Dermatology Hospital of the University of Pennsylvania Philadelphia Pennsylvania;

    Department of Surgery Division of Urology Hospital of the University of Pennsylvania;

    Department of Surgery Division of Urology Hospital of the University of Pennsylvania;

    Department of Dermatology Hospital of the University of Pennsylvania Philadelphia Pennsylvania;

    Department of Dermatology Hospital of the University of Pennsylvania Philadelphia Pennsylvania;

    Department of Dermatology Hospital of the University of Pennsylvania Philadelphia Pennsylvania;

    Department of Dermatology Hospital of the University of Pennsylvania Philadelphia Pennsylvania;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 皮肤病学与性病学;
  • 关键词

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