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首页> 外文期刊>Dermatologic surgery >Injectable Platelet-, Leukocyte-, and Fibrin-Rich Plasma (iL-PRF) in the Management of Androgenetic Alopecia.
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Injectable Platelet-, Leukocyte-, and Fibrin-Rich Plasma (iL-PRF) in the Management of Androgenetic Alopecia.

机译：可注射的血小板，白细胞和纤维蛋白和富含纤维蛋白的血浆（IL-PRF）在嗜血生殖症的管理中。

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The role of enriched autologous plasmas in androgenetic alopecia (AGA) management is emerging in recent literature. In this prospective study, the authors aimed to confirm that the induction of a minor local trauma immediately followed by injections of an enriched plasma made of a strongly concentrated platelet fraction, a robust white cell presence, concentrated fibrinogen, and other plasma proteins (injectable leukocyte platelet-rich fibrin [iL-PRF]) could be able to produce positive clinical results in patients with AGA. A 2-injection regimen was instituted, with a 3-month interval between the 2 interventions. A treatment group (TG) and a control group (CG) were instituted. Macrophotographs were taken at baseline and after 6 months, and rated by 5-people expert panel (blinded to this assignment) using the 15-point scale proposed by Jaeschke to evaluate the clinical change. Overall, TG showed better scores compared with the CG in all 5 classes of global physician assessment at baseline, all age groups, and in both sexes, and such differences always reached statistical significance. A greater severity at baseline showed a larger improvement after treatment in the TG. This study provides preliminary evidence that the biological composition of the iL-PRF is of crucial importance in ensuring a good degree of clinical efficacy in patients with AGA.
机译：富集的自体等离子体在近期文献中富集血管生成血症（AGA）管理中的作用。在这项前瞻性研究中，作者旨在证实，立即诱导小局部创伤，然后立即注射由强浓缩的血小板部分，鲁棒的白细胞存在，浓缩纤维蛋白原和其他血浆蛋白质制成的富集的血浆（可注射白细胞富含血小板的纤维蛋白[IL-PRF]）可以能够在AGA患者中产生阳性临床结果。提出了2注射方案，在2个干预措施之间具有3个月间隔。制定了治疗组（TG）和对照组（CG）。 Macrophotographs是在基线和6个月后拍摄的，并使用Jaeschke提出的15分尺度评估临床变革的15人专家小组（盲目地盲目）。总体而言，TG与基线，所有年龄组和两性的所有5级全球医生评估中的CG相比表现出更好的分数，并且这种差异总是达到统计显着性。在基线上具有更大的严重程度在TG治疗后显示出更大的改善。本研究提供了初步证据，即IL-PRF的生物学组成对于确保AGA患者的良好程度的临床疗效至关重要。

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