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Fetal alcohol spectrum disorders: new perspectives on diagnosis and intervention.

机译:胎儿酒精频谱异常:诊断和干预的新观点。

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摘要

It has been nearly four decades since Jones and Smith (1973) and Jones et al. (1973,1974) published their landmark articles reporting their observation of a constellation of identifiable birth defects in infants of women who drank alcohol heavily during pregnancy. They found that the combined presence of pre- and postnatal growth deficits, microcephaly (a proxy measure of central nervous system defects), and a pattern of subtle abnormalities in facial features were associated with heavy maternal alcohol use and was termed fetal alcohol syndrome (FAS). Although similar observations were published in French by Lemoine et al. (1968), the publications by Jones and Smith (1973) and Jones et al. (1973, 1974) were central to bringing scientific and social attention to the potentially harmful effects of alcohol consumption during pregnancy.
机译:自从Jones和Smith(1973)和Jones等人以来,已经过去了近40年。 (1973,1974)发表了具有里程碑意义的文章,报道了他们观察到在怀孕期间大量饮酒的妇女婴儿中可识别的先天缺陷群。他们发现,合并的产前和产后生长缺陷,小头畸形(中枢神经系统缺陷的替代指标)和面部特征的细微异常模式与孕妇大量饮酒有关,被称为胎儿酒精综合症(FAS) )。尽管Lemoine等人在法国发表了类似的观点。 (1968),琼斯和史密斯(1973)和琼斯等人的出版物。 (1973,1974)是引起科学和社会关注怀孕期间饮酒的潜在有害影响的关键。

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