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首页> 外文期刊>Diagnostic cytopathology >Diagnostic utility of urine cytology in detection of decoy cells in renal transplant patients: Report of five cases and review of literature
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Diagnostic utility of urine cytology in detection of decoy cells in renal transplant patients: Report of five cases and review of literature

机译：尿液细胞学检测肾移植患者诱饵细胞的诊断效用：五种病例报告及文学审查

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摘要

Abstract BK polyoma virus (PV) is one of the commonest post‐transplant viral infections, affecting approximately 15% of renal transplantation recipients, leading to graft failure in more than half of cases. The epithelial cells with polyoma viral inclusions in urine cytology specimens are termed “decoy cells” to caution pathologists not to misdiagnose these cells as cancer cells. The infected cells in urinary sediments are characterized by enlarged nucleus, basophilic intranuclear homogenous inclusions, and ground glass chromatin, which may cause diagnostic error in urine cytology. We report five cases of renal transplant patients, in which urine sample was positive for decoy cells. Routine urine cytology of post renal transplant patients with worsening renal function is a useful screening procedure to rule out PV reactivation, before ascertaining transplant rejection. Its cost‐effectiveness in addition to the short processing time makes it an invaluable tool in the evaluation of transplant recipients with symptoms suggestive of graft rejection.
机译：摘要BK Polyoma病毒（PV）是最常见的移植后病毒感染之一，影响大约15％的肾移植受体，导致超过一半的患者移植失败。具有尿液细胞学样本中的具有聚类病毒夹杂物的上皮细胞被称为“诱饵细胞”，以便小心病理学医生不误解这些细胞作为癌细胞。尿沉沉积物中的感染细胞的特征在于髓核增大，嗜碱性肿瘤均匀夹杂物和地面玻璃染色质，这可能导致尿液细胞学中的诊断误差。我们报告了五例肾移植患者，其中尿液样品对于诱饵细胞是阳性的。肾功能恶化肾功能后肾移植患者的常规尿液细胞学是一种有用的筛选程序，以便在确定移植排出之前排除PV再活化。其成本效益除了短暂的处理时间之外，还具有在移植受者评估移植受者的宝贵工具，提示移植物排斥。

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