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首页> 外文期刊>Diagnostic microbiology and infectious disease >Epidemiology of human respiratory viruses in children with acute respiratory tract infection in a 3-year hospital-based survey in Northern Italy
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Epidemiology of human respiratory viruses in children with acute respiratory tract infection in a 3-year hospital-based survey in Northern Italy

机译：急性呼吸道感染儿童人类呼吸道病毒流行病学在意大利3年的医院调查中的急性呼吸道感染

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摘要

Acute respiratory tract infections (ARTIs) are among the leading causes of morbidity and mortality in children. The viral etiology of ARTIs was investigated over 3 years (October 2012-September 2015) in 2575 children in Parma, Italy, using indirect immunofluorescent staining of respiratory samples for viral antigens, cell culture, and molecular assays. Respiratory viruses were detected in 1299 cases (50.44%); 1037 (79.83%) were single infections and 262 (20.17%) mixed infections. The highest infection incidence was in children aged >6 months to <= 3 years (57.36%). Human respiratory syncytial virus (27.12%) and human adenovirus (23.58%) were the most common viruses identified. The virus detection rate decreased significantly between the first and third epidemic season (53.9% vs. 43.05%, P < 0.0001). The simultaneous use of different diagnostic tools allowed us to identify a putative viral etiology in half the children examined and to provide an estimate of the epidemiology and seasonality of respiratory viruses associated with ARTIs. (C) 2019 Elsevier Inc. All rights reserved.
机译：急性呼吸道感染（ARTIS）是儿童发病率和死亡率的主要原因。 Artis的病毒病因在意大利帕尔马帕尔马帕尔马的2575名儿童（2012年10月），使用间接免疫荧光染色，用于病毒抗原，细胞培养和分子测定。在1299例（50.44％）中检测到呼吸病毒; 1037（79.83％）是单一感染和262（20.17％）的混合感染。最高的感染发病率为1岁的儿童> 6个月至<= 3岁（57.36％）。人类呼吸合胞病毒（27.12％）和人腺病毒（23.58％）是​​最常见的病毒。第一个和第三疫情季节（53.9％与43.05％，P <0.0001）之间的病毒检测率显着下降。同时使用不同的诊断工具允许我们鉴定审查的儿童的一半药物病毒病因，并提供与Artis相关的呼吸道病毒的流行病学和季节性的估计。 （c）2019 Elsevier Inc.保留所有权利。

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