Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy

Zhao Jing; Xu Youwei; Wang Changyuan; Ding Yanfang; Chen Manyu; Wang Yifei; Peng Jinyong; Li Lei; Lv Li

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Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy

机译：SoluPlus / TPGS混合胶束用于癌症治疗中的二十次递送

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摘要

Background: Dioscin has shown cytotoxicity against cancer cells, but its poor solubility and stability have limited its clinical application. In this study, we designed mixed micelles composed of TPGS and Soluplus (R) copolymers entrapping the poorly soluble anticancer drug dioscin.

机译：背景：Dioscin显示出对癌细胞的细胞毒性，但其溶解度差和稳定性有限限制其临床应用。在这项研究中，我们设计了由诱捕难以溶解的抗癌药物的TPGS和Soluplus（R）共聚物组成的混合胶束。

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来源
《Drug development and industrial pharmacy》 |2017年第12期|共8页
作者
Zhao Jing; Xu Youwei; Wang Changyuan; Ding Yanfang; Chen Manyu; Wang Yifei; Peng Jinyong; Li Lei; Lv Li;
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作者单位

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

Dalian Med Univ Sch Pharm Dalian Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Dioscin; mixed micelles; TPGS; Soluplus; cancer therapy;

机译：Dioscin;混合胶束;TPGS;soluplus;癌症治疗;

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专利

1. Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy [J] . Zhao Jing, Xu Youwei, Wang Changyuan, Drug development and industrial pharmacy . 2017,第7a12期

机译：SoluPlus / TPGS混合胶束用于癌症治疗中的二十次递送
2. Amphiphilic copolymer and TPGS mixed magnetic hybrid micelles for stepwise targeted co-delivery of DOX/TPP–DOX and image-guided chemotherapy with enhanced antitumor activity in liver cancer [J] . Xiaoju Shi, Guoyue Lv, Xiaodong Sun, RSC Advances . 2017,第41期

机译：两亲共聚物和TPGS混合磁混合胶束用于逐步靶向共递送DOX / TPP–DOX和图像引导化疗，增强了肝癌的抗肿瘤活性
3. Amphiphilic copolymer and TPGS mixed magnetic hybrid micelles for stepwise targeted co-delivery of DOX/TPP–DOX and image-guided chemotherapy with enhanced antitumor activity in liver cancer [J] . Xiaoju Shi, Guoyue Lv, Xiaodong Sun, RSC Advances . 2017,第41期

机译：两亲共聚物和TPGS混合磁混合胶束用于逐步靶向共递送DOX / TPP–DOX和图像引导化疗，增强了肝癌的抗肿瘤活性
4. POLY (ETHYLENE OXIDE)-POLY(ε-CAPROLACTONE) MICELLES IN DIFFERENT MORPHOLOGIES: ADVANTAGES OF WORM-LIKE MICELLES FOR DELIVERY OF PACLITAXEL IN LUNG CANCER THERAPY [C] . Shenshen Cai, Tamara Minko, Dennis E. Discher Controlled Release Society Annual Meeting and Exposition . 2007

机译：不同形态的聚（环氧乙烷）-聚（ε-己内酯）胶束：蠕虫状胶束在肺癌治疗中递送帕西他赛的优势
5. Polymeric Micelles for Combination Drug Delivery in Cancer Therapy. [D] . Zeng, San. 2015

机译：用于癌症治疗中组合药物递送的聚合物胶束。
6. Targeted delivery of ginsenoside compound K using TPGS/PEG-PCL mixed micelles for effective treatment of lung cancer [O] . Lei Yang, Zhenghai Zhang, Jian Hou, 2017

机译：使用TPGS / PEG-PCL混合胶束靶向输送人参皂苷K以有效治疗肺癌
7. Targeted delivery of ginsenoside compound K using TPGS/PEG-PCL mixed micelles for effective treatment of lung cancer [O] . Lei Yang, Zhenhai Zhang, Jian Hou, 2017

机译：使用TPGS / PEG-PCL混合胶束针对人参皂甙化合物K进行靶向递送肺癌

Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy

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