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首页> 外文期刊>AJR: American Journal of Roentgenology : Including Diagnostic Radiology, Radiation Oncology, Nuclear Medicine, Ultrasonography and Related Basic Sciences >Diagnostic accuracy and recall rates for digital mammography and digital mammography combined with one-view and two-view tomosynthesis: Results of an enriched reader study
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Diagnostic accuracy and recall rates for digital mammography and digital mammography combined with one-view and two-view tomosynthesis: Results of an enriched reader study

机译：数字化X线摄影和数字化X线摄影结合单视图和两视图断层合成的诊断准确性和召回率：丰富的读者研究结果

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OBJECTIVE. The purpose of this study was to compare two methods of combining tomosynthesis with digital mammography by assessing diagnostic accuracy and recall rates for digital mammography alone and digital mammography combined with one-view tomosynthesis SUBJECTS AND METHODS. Three hundred ten cases including biopsy-proven malignancies (51), biopsy-proven benign findings (47), recalled screening cases (138), and negative screening cases (74) were reviewed by 15 radiologists sequentially using digital mammography, adding one-view tomosynthesis, and then two-view tomosynthesis. Cases were assessed for recall and assigned a BI-RADS score and probability of malignancy for each imaging method. Diagnostic accuracy was assessed using receiver operating characteristic (ROC) analysis. Screening recall rates were compared using pooled logistical regression analysis. A p value of < 0.0167 was considered significant. RESULTS. The area under the ROC curve (AUC) for digital mammography (DM), DM plus one-view tomosynthesis, and DM plus two-view tomosynthesis was 0.828, 0.864, and 0.895, respectively. Both one-view and two-view tomosynthesis plus DM were significantly better than DM alone (Δ AUCs 0.036 [p = 0.009] and 0.068 [p < 0.001]). Average noncancer recall rates for digital mammography, DM plus one-view tomosynthesis, and DM plus two-view tomosynthesis were 44.2%, 27.2%, and 24.0%, respectively. Combined with DM, one-view and two-view tomosynthesis both showed significantly lower noncancer recall rates than digital mammography alone ( p < 0.001). Digital mammography with two-view tomosynthesis showed a significantly lower recall rate than digital mammography with one-view tomosynthesis ( p < 0.001). Diagnostic accuracy for dense (Δ AUC, 0.091%; p < 0.001) and nondense (Δ AUC, 0.035%; p = 0.001) breasts improved with DM plus two-view tomosynthesis compared with digital mammography alone. Compared with digital mammography, diagnostic sensitivity for invasive cancers increased with the addition of both one-view (Δ12.0%, p < 0.001) and two-view (Δ21.7%, p < 0.001) tomosynthesis. CONCLUSION. The addition of one-view tomosynthesis to conventional digital mammography improved diagnostic accuracy and reduced the recall rate; however, the addition of two-view tomosynthesis provided twice the performance gain in diagnostic accuracy while further reducing the recall rate. and two-view tomosynthesis.
机译：目的。这项研究的目的是通过评估单独的数字化X线摄影术和数字化X线摄影术与单视图断层合成技术相结合的诊断准确性和召回率，来比较结合断层摄影与数字化X线摄影术的两种方法。 15位放射科医生使用数字化X线乳房X线摄影术依次检查了包括活检证实的恶性肿瘤（51），活检证实的良性发现（47），召回的筛查病例（138）和阴性筛查病例（74）在内的310例病例，断层合成，然后进行两视图断层合成。对病例进行召回评估，并为每种影像学方法分配BI-RADS评分和恶性概率。使用接收器工作特性（ROC）分析评估诊断准确性。使用汇总逻辑回归分析比较筛查召回率。 p值<0.0167被认为是显着的。结果。数字乳腺摄影（DM），DM加单断层成像和DM加双断层成像的ROC曲线（AUC）下的面积分别为0.828、0.864和0.895。一视图和二视图层析合成加DM均显着优于单独使用DM（ΔAUCs为0.036 [p = 0.009]和0.068 [p <0.001]）。数字化乳腺摄影，DM加单断层断层扫描和DM加双断层断层摄像的平均非癌回忆率分别为44.2％，27.2％和24.0％。与DM结合使用时，一断层和二断层断层成像均显示出比单独的乳腺X线摄影术更低的非癌召回率（p <0.001）。具有X线断层扫描的数字化乳腺X线照片显示的召回率显着低于具有单层断层扫描的数字化X线乳房摄影术（p <0.001）。与仅使用数字乳腺X线断层扫描相比，DM加双视野断层合成可以改善致密（ΔAUC，0.091％; p <0.001）和不密集（ΔAUC，0.035％; p = 0.001）乳房的诊断准确性。与数字化乳腺X线摄影术相比，同时进行单断层扫描（Δ12.0％，p <0.001）和两断层扫描（Δ21.7％，p <0.001）时，浸润性癌的诊断敏感性增加。结论。在传统的数字化乳腺X线摄影术中增加了单眼断层合成技术，提高了诊断准确性并降低了召回率;但是，增加了两视图断层合成技术可以使诊断准确性提高两倍，同时进一步降低召回率。和两视图断层合成。

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