Advances in measuring single-cell pharmacology in vivo

Vinegoni Claudio; Dubach J. Matthew; Thurber Greg M.; Miller Miles A.; Mazitschek Ralph; Weissleder Ralph

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Advances in measuring single-cell pharmacology in vivo

机译：测量体内单细胞药理学的进展

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摘要

Measuring key pharmacokinetic and pharmacodynamic parameters in vivo at the single cell level is likely to enhance drug discovery and development. In this review, we summarize recent advances in this field and highlight current and future capabilities.

机译：在单细胞水平上测量体内体内的主要药代动力学和药效学参数可能会增强药物发现和发展。在本次审查中，我们总结了该领域的最新进展，并突出了当前和未来的能力。

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来源
《Drug discovery today》 |2015年第9期|共6页
作者
Vinegoni Claudio; Dubach J. Matthew; Thurber Greg M.; Miller Miles A.; Mazitschek Ralph; Weissleder Ralph;
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作者单位

Massachusetts Gen Hosp Ctr Syst Biol Boston MA 02114 USA;

Massachusetts Gen Hosp Ctr Syst Biol Boston MA 02114 USA;

Univ Michigan Dept Biomed Engn Dept Chem Engn Ann Arbor MI 48109 USA;

Massachusetts Gen Hosp Ctr Syst Biol Boston MA 02114 USA;

Massachusetts Gen Hosp Ctr Syst Biol Boston MA 02114 USA;

Massachusetts Gen Hosp Ctr Syst Biol Boston MA 02114 USA;

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原文格式 PDF
正文语种 eng
中图分类药学;
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1. Advances in measuring single-cell pharmacology in vivo [J] . Vinegoni Claudio, Dubach J. Matthew, Thurber Greg M., Drug discovery today . 2015,第9期

机译：体内单细胞药理学测量的进展
2. Advances in measuring single-cell pharmacology in vivo [J] . Claudio Vinegoni, J. Matthew Dubach, Greg M. Thurber, Drug discovery today . 2015,第2期

机译：测量体内单细胞药理学的进展
3. Advances in measuring single-cell pharmacology in vivo [J] . Claudio Vinegoni, J. Matthew Dubach, Greg M. Thurber, Drug discovery today . 2015,第5a12期

机译：测量体内单细胞药理学的进展
4. Establishing a Novel In Vivo Platform to Interrogate the Effects of Pharmacologic and Molecularly Targeted Modulation of CDK5 in the Invasive and Metastatic Potential of Medulloblastoma in Live Experimental Animals [C] . A. Petrosiute, J. Myers, J. Nthale, International Metallographic Society Annual meeting;Microscopy Society of America Annual Meeting;Microanalysis Society Annual meeting . 2011

机译：建立一个新颖的体内平台，以询问药理学和分子靶向调节CDK5在活实验动物的髓母细胞瘤侵袭和转移潜能中的作用
5. Advancing the pharmacological control of ovarian development to enhance fertility of lactating dairy cows. [D] . Martins, Joao Paulo Nascimento. 2016

机译：推进卵巢发育的药理控制，以提高泌乳奶牛的生育能力。
6. Advances in measuring single-cell pharmacokinetics and pharmacology in vivo [O] . Claudio Vinegoni, John M. Dubach, Greg M. Thurber, -1

机译：体内单细胞药代动力学和药理学测量的进展
7. Advances in measuring single-cell pharmacology in vivo [O] . Claudio Vinegoni, J. Matthew Dubach, Greg M. Thurber, 2015

机译：在体内测量单细胞药理学的进展

Advances in measuring single-cell pharmacology in vivo

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