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首页> 外文期刊>Drug and alcohol review >Understanding an emerging treatment population: Protocol for and baseline characteristics of a prospective cohort of people receiving treatment for pharmaceutical opioid dependence
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Understanding an emerging treatment population: Protocol for and baseline characteristics of a prospective cohort of people receiving treatment for pharmaceutical opioid dependence

机译：理解新兴待遇人口：接受药物阿片类药物依赖治疗的潜在群体的议定书和基线特征

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Abstract Introduction and Aims Despite large increases in pharmaceutical opioid dependence and related mortality, few studies have focused on the characteristics and treatment experiences of those with pharmaceutical opioid dependence. We describe the formation of a prospective cohort of people receiving treatment for pharmaceutical opioid dependence and describe their baseline characteristics. Design and Methods People who had entered treatment for pharmaceutical opioid dependence ( n = 108) were recruited through drug treatment services in New South Wales, Australia. We describe baseline characteristics of those that commenced pharmaceutical opioids for pain or other reasons and conducted a thematic analysis of responses regarding their treatment experience. Results Mean age was 41 years (SD 11), half were male (48%). Just over half reported lifetime heroin use (57%). Oxycodone (49%) and codeine (29%) were the most common opioids reported. Most (85%) reported past‐year problematic pain, 38% reported chronic pain. Half (52%) reported moderate to severe depression symptoms. Most (66%) commenced opioids for pain, and this group were older, less likely to report a previous overdose and less likely to report use of illicit drugs compared to those commencing for other reasons. Five themes related to treatment expectations: (i) stigma; (ii) the restrictive nature of treatment; (iii) knowledge; (iv) pain; and (v) positive experience with buprenorphine. Discussion and Conclusions This study describes the complexities in an important emerging treatment population of pharmaceutical opioid‐dependent people. Findings highlights that addressing knowledge and perceptions around treatment may be critical to address the rising mortality associated with pharmaceutical opioid dependence.
机译：摘要提出和目标尽管药物阿片类药物依赖性和相关死亡率大幅增加，但很少有研究专注于药物阿片类药物依赖的特征和治疗经验。我们描述了接受药物阿片类药物依赖的治疗的预期队列的形成，并描述了它们的基线特征。通过澳大利亚新南威尔士州新南威尔士州的药物治疗服务招募了对药物阿片类药物依赖（n = 108）进行治疗的设计和方法。我们描述了那些开始药物阿片类药物的基线特征，用于疼痛或其他原因，对其治疗经验进行了对响应的主题分析。结果平均年龄为41岁（SD 11），一半是男性（48％）。刚刚超过一半的终身海洛因使用（57％）。羟考酮（49％）和可待因（29％）是最常见的阿片类药物。大多数（85％）报告过去一年的问题疼痛，报告慢性疼痛38％。一半（52％）报告中度至严重抑郁症状。大多数（66％）开始疼痛的阿片类药物，而该组年龄较大，较少可能报告以前过量的过量，并且与其他原因的开始相比，延长有可能报告使用非法药物的使用。与治疗期望相关的五个主题：（i）耻辱; （ii）治疗的限制性; （iii）知识; （iv）疼痛; （v）与Buprenorphine的积极经验。讨论和结论本研究描述了在依赖药物依赖的药物的重要新出现的治疗群体中的复杂性。调查结果强调，解决围绕治疗的知识和看法可能对解决与药物阿片类药物依赖相关的升高死亡率至关重要。

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  • 来源
    《Drug and alcohol review》 |2018年第7期|共10页
  • 作者

    Nielsen Suzanne; Lintzeris Nicholas; Murnion Bridin; Degenhardt Louisa; Bruno Raimondo; Haber Paul; Johnson Jennifer; Hardy Mark; Ling Stephen; Saddler Craig; Dunlop Adrian; Demirkol Apo; Silsbury Catherine; Phung Nghi; Houseman Jennie; Larance Briony;

  • 作者单位

    National Drug and Alcohol Research CentreUNSW SydneySydney Australia;

    South East Sydney Local Health District Drug and Alcohol ServicesSydney Australia;

    Discipline of Addiction MedicineUniversity of SydneySydney Australia;

    National Drug and Alcohol Research CentreUNSW SydneySydney Australia;

    School of PsychologyUniversity of TasmaniaHobart Australia;

    Discipline of Addiction MedicineUniversity of SydneySydney Australia;

    University Centre for Rural Health – North CoastUniversity of SydneyLismore Australia;

    Drug and Alcohol ServicesNorthern Sydney Local Health DistrictSydney Australia;

    Drug and Alcohol Clinical ServicesHunter New England Local Health DistrictNewcastle Australia;

    Drug and Alcohol Clinical ServicesHunter New England Local Health DistrictNewcastle Australia;

    Drug and Alcohol Clinical ServicesHunter New England Local Health DistrictNewcastle Australia;

    South East Sydney Local Health District Drug and Alcohol ServicesSydney Australia;

    Drug Health Services Western Sydney Local Health District SydneyAustralia;

    Drug Health Services Western Sydney Local Health District SydneyAustralia;

    Drug and Alcohol ServicesNorthern Sydney Local Health DistrictSydney Australia;

    National Drug and Alcohol Research CentreUNSW SydneySydney Australia;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药学;
  • 关键词

    pharmaceutical opioid; codeine; oxycodone; buprenorphine; treatment;

    机译：药物阿片类化合物;可待因;羟考酮;丁丙诺啡;治疗;

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