Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology

Schreiber Stefanie; Schreiber Frank; Lockhart Samuel N.; Horng Andy; Bejanin Alexandre; Landau Susan M.; Jagust William J.

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Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology

机译：具有疑似非阿尔茨海默病病理生理学的轻度认知障碍中的阿尔茨海默病签名神经变性和ApoE基因型

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IMPORTANCE There are conflicting results claiming that Alzheimer disease signature neurodegeneration may be more, less, or similarly advanced in individuals with beta-amyloid peptide (A beta)-negative (A beta-) suspected non-Alzheimer disease pathophysiology (SNAP) than in A beta-positive (A beta+) counterparts.

机译：重要性突破了结果的矛盾的结果，即β-淀粉样肽（Aβ）疑似非阿尔茨米默病病理生理学（SNAP）中的个体中的β-淀粉样肽（Aβ）的个体中的种族性疾病签名神经变性可能更加，较少，或类似地前进。 β-阳性（β+）对应物。

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《JAMA neurology》 |2017年第6期|共10页
作者
Schreiber Stefanie; Schreiber Frank; Lockhart Samuel N.; Horng Andy; Bejanin Alexandre; Landau Susan M.; Jagust William J.;
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作者单位

Univ Calif Berkeley Helen Wills Neurosci Inst 132 Barker Hall Mail Code 3190 Berkeley CA 94720;

Otto Von Guericke Univ Dept Neurol Magdeburg Germany;

Univ Calif Berkeley Helen Wills Neurosci Inst 132 Barker Hall Mail Code 3190 Berkeley CA 94720;

Univ Calif Berkeley Helen Wills Neurosci Inst 132 Barker Hall Mail Code 3190 Berkeley CA 94720;

Univ Calif San Francisco Dept Neurol Memory &

Aging Ctr San Francisco CA 94143 USA;

Univ Calif Berkeley Helen Wills Neurosci Inst 132 Barker Hall Mail Code 3190 Berkeley CA 94720;

Univ Calif Berkeley Helen Wills Neurosci Inst 132 Barker Hall Mail Code 3190 Berkeley CA 94720;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
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1. Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology [J] . Schreiber Stefanie, Schreiber Frank, Lockhart Samuel N., JAMA neurology . 2017,第6期

机译：具有疑似非阿尔茨海默病病理生理学的轻度认知障碍中的阿尔茨海默病签名神经变性和ApoE基因型
2. Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study [J] . Burnham Samantha C., Bourgeat Pierrick, Dore Vincent, Lancet Neurology . 2016,第10期

机译：具有可疑的非阿尔茨海默氏病病理生理学（SNAP）或阿尔茨海默氏病病理学的认知健康老年人的临床和认知轨迹：一项纵向研究
3. Hippocampal and Clinical Trajectories of Mild Cognitive Impairment with Suspected Non-Alzheimer's Disease Pathology [J] . Chung Jun Ku, Plitman Eric, Nakajima Shinichiro, Journal of Alzheimer's disease: JAD . 2017,第3期

机译：具有疑似非阿尔茨海默病病理的温和认知障碍的海马和临床轨迹
4. Early Detection of Mild Cognitive Impairment and Mild Alzheimer's Disease in Elderly using CBF Activation during Verbally-based Cognitive Tests [C] . Shohei Kato, Hidetoshi Endo, Risako Nagata, International Conference on Health Informatics . 2014

机译：在基于口头的认知测试期间使用CBF激活的老年人患者轻度认知障碍和轻度阿尔茨海默病的早期发现
5. Biological Changes in the Development and Neurodegeneration of Mild Cognitive Impairment and Alzheimer's Disease. [D] . Ayan-Oshodi, Mosun A. 2013

机译：轻度认知障碍和阿尔茨海默氏病的发展和神经变性的生物学变化。
6. Distinct Brain Functional Impairment Patterns Between Suspected Non-Alzheimer Disease Pathophysiology and Alzheimer’s Disease: A Study Combining Static and Dynamic Functional Magnetic Resonance Imaging [O] . Zheyu Li, Kaicheng Li, Xiao Luo, 2020

机译：疑似非阿尔茨海默病病理生理和阿尔茨海默病之间的明显脑功能损伤模式：静态动态功能磁共振成像的研究
7. A Comprehensive Visual Rating Scale for Predicting Progression from Mild Cognitive Impairment to Dementia in Patients with Alzheimer's Pathology or Suspected Non-Alzheimer's Pathology [O] . Sang Won Park, Seongheon Kim, Jeonghoon Park, 2020

机译：一种全面的视觉评级规模，用于预测对阿尔茨海默病病病理或疑似非阿尔茨海默病理论的轻度认知障碍对痴呆症的进展

Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology

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