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Estimation of O-2 and CO2 solubility in microbial culture media

机译:估计O-2和CO2在微生物培养基中的溶解度

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摘要

A simple model for predicting gas solubilities of O-2 and CO2 at low pressure and near ambient temperature in solutions of salts, sugars, and organic solvents (alcohols, ketones, ethers, aldehydes, etc.) is proposed. It is derived from the Van Laar assumptions and takes account of size differences between molecules in solution by their volumetric fraction. It is a group contribution model where anions and cations are considered as groups and other molecules are treated as in the UNIFAC (UNIQUAC Functional group Activity Coefficients) procedure. Pseudo-Henry's constants for groups were determined using solubility data in aqueous solutions containing only one salt, one sugar, or one organic compound at 25 degrees C. The predictive performance of the model was evaluated by comparison with experimental data using multicomponent aqueous salt-sugar mixtures. The model was used to estimate solubilities of oxygen and carbon dioxide in fermentation media.
机译:提出了一个简单的模型,用于预测盐和糖,有机溶剂(醇,酮,醚,醛等)在低压和接近环境温度下O-2和CO2的气体溶解度。它是根据Van Laar假设得出的,并考虑了溶液中分子之间的体积差异(按体积分数)。这是一种基团贡献模型,其中阴离子和阳离子被视为基团,其他分子则按照UNIFAC(UNIQUAC官能团活度系数)程序进行处理。使用在25°C下仅含一种盐,一种糖或一种有机化合物的水溶液中的溶解度数据确定组的伪亨利常数。通过与使用多组分盐糖水溶液的实验数据进行比较,评估模型的预测性能混合物。该模型用于估计发酵培养基中氧气和二氧化碳的溶解度。

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