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首页> 外文期刊>Journal of Analytical Toxicology >Fatalities Involving Carfentanil and Furanyl Fentanyl: Two Case Reports
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Fatalities Involving Carfentanil and Furanyl Fentanyl: Two Case Reports

机译：涉及Carfentanil和Furanyl Fentanyl的死亡事件：两种报告

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Carfentanil is a fentanyl analog frequently used in large animal veterinary medicine. Recently, carfentanil has been discovered in postmortem and antemortem cases throughout the United States in the heroin supply either alone or mixed with heroin and/or other fentanyl analogs. The potency of carfentanil is similar to 10,000 times greater than morphine and 100 times greater than fentanyl. In two recent cases, carfentanil was identified and ruled to be the cause of death, either alone or in combination with other drugs. Case 1 involved a known heroin user. He was discovered slumped over in a running van blocking the bays of a carwash. Two syringes, a spoon with cotton and residue and a yellow baggie of powder were found in the van. Case 2 involved a man living in a tent in a park with his mother. He was last heard from by a sister via phone who stated he sounded very intoxicated and by his mother who noted him to be "itching all over" and upset over his girlfriend. When the mother returned from work, she discovered him unresponsive with a small baggie of brown powder next to him. Routine drug and volatile screening tests were performed on heart blood using headspace gas chromatography, immunoassay and gas chromatography mass spectrometry methods. Results from initial testing on both cases did not have any significant toxicological findings. However, due to the history, scene photos, toxicological findings in blood and urine and analysis of the drug paraphernalia on one of the cases which identified carfentanil and furanyl fentanyl, fentanyl analogues were suspected. Heart blood was sent to a reference laboratory for carfentanil and furanyl fentanyl analysis. Case 1 had a carfentanil concentration of 1.3 ng/mL and a furanyl fentanyl concentration of 0.34 ng/mL. Case 2 had a carfentanil concentration of 0.12 ng/mL.
机译：Carfentanil是一种经常用于大型动物兽医药物的芬太尼蛋白。最近，Carfentanil已在海洛因在海洛因和海洛因和/或其他芬太尼类似物混合的海洛因供应中发现了Carfentanil。 Carfentanil的效力比吗啡的10,000倍，比芬太尼大100倍。在最近的两个病例中，鉴定了胭脂红乃，并裁定为死亡的原因，单独或与其他药物组合。案例1涉及已知的海洛因用户。他被发现陷入困境的范围内，阻挡了洗车的海湾。在面包车中发现了两个注射器，用棉花和残留物和粉末的黄色袋子。案例2涉及与他的母亲在公园里生活在帐篷里的人。他最后一次听到姐姐通过电话听到他的电话，他听起来非常陶醉，并由他的母亲注意到他“痒过于痒”并对他的女朋友感到沮丧。当母亲从工作归还时，她发现他没有对他旁边的一个小棕色粉的小袋子无反应。使用顶空气相色谱法，免疫测定和气相色谱法质谱法对心血进行常规药物和挥发性筛选试验。两种病例的初始测试结果没有任何显着的毒理学发现。然而，由于历史，场景照片，血液和尿液中的毒理学发现以及对鉴定胭脂醛和呋喃基芬太尼的病例中的一种病例分析，怀疑芬太尼类似物。心血血液被送到Carfentanil和Furanyl芬太尼分析的参考实验室。案例1具有1.3ng / ml的胰岛浓度为1.3ng / ml，富烷基浓度为0.34ng / ml。案例2具有0.12ng / ml的胰岛浓度。

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