首页> 外文期刊>Journal of affective disorders >Difference in Temperament and Character Inventory scores between depressed patients with bipolar II and unipolar major depressive disorders.
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Difference in Temperament and Character Inventory scores between depressed patients with bipolar II and unipolar major depressive disorders.

机译:抑郁症二极管二极管和单极性抑郁障碍患者气质和性格库存分数差异。

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BACKGROUND: Although some core personality variables are known to be characteristic of unipolar or bipolar depression, few studies have compared the personality profile between these two disorders. METHODS: Temperament and Character Inventory (TCI) was employed to assess the personality of 36 depressed patients with bipolar II disorder (BPII), 90 patients with unipolar major depressive disorder (UP), and 306 healthy controls. The TCI was administered during the depressive episode in BPII and UP patients so that the results can be applied in a clinical setting. RESULTS: Significantly higher scores in harm avoidance (p<0.0001) and lower scores in self-directedness (p<0.0001) and cooperativeness (p<0.05) were observed in both BPII and UP patients compared to controls. Lower novelty seeking in UP patients compared to BPII patients and controls was observed in females (p<0.0001, p<0.01, respectively). A significant difference in self-transcendence score was observed between BPII and UP patients in females (p<0.0005), with higher scores in BPII (p=0.009) and lower scores in UP (p=0.046) patients compared to controls. A logistic regression model predicted BPII in depressed females based on novelty seeking and self-transcendence scores with a sensitivity of 89% and a specificity of 73%, but did not accurately predict BPII in males. LIMITATIONS: Patients in our study were limited to those receiving outpatient treatments, and bipolar patients were limited to those with BPII. CONCLUSIONS: Novelty seeking and self-transcendence scores of TCI might be useful in the differentiation of UP and BPII in female patients.
机译:背景:虽然已知一些核心个性变量是单极或双极抑制的特征,但很少有研究比较了这两个疾病之间的人格概况。方法:使用气质和性格库存(TCI),用于评估36例抑郁症患者的双相II疾病(BPII),90名单极性抑郁症(UP)和306名健康对照组的人格。在BPII和UP患者的抑郁发作期间施用TCI,以便可以在临床环境中应用结果。结果:在BPII和UP患者中,在BPII和UP患者中观察到避免伤害(P <0.0001)的分数明显较高(P <0.0001),并且在BPII和UP患者中观察到的分数(P <0.0001)和合作(P <0.05)。与BPII患者的患者较低的新颖性寻求患者,在女性中观察到(分别为P <0.0001,P <0.01)。在雌性和女性患者(P <0.0005)之间观察到自我转生评分的显着差异,与对照相比,BPII(P = 0.009)中得分更高(P = 0.009),并降低得分(P = 0.046)患者。基于新颖的寻求和自我超越评分的抑郁症患者预测了BPII的逻辑回归模型,其敏感性为89%,特异性为73%,但在雄性中没有准确地预测BPII。局限性:我们研究的患者仅限于接受门诊治疗的患者,并且双极患者仅限于BPII的那些。结论:TCI的新颖寻求和自我超越评分在女性患者中的UP和BPII的分化中可能有用。

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