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首页> 外文期刊>Journal of Animal Physiology and Animal Nutrition >Alpha-lipoic acid improves the reproduction performance of breeder hens during the late egg-laying period
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Alpha-lipoic acid improves the reproduction performance of breeder hens during the late egg-laying period

机译：α-硫辛酸在晚期鸡蛋铺设期间提高了育种母鸡的再现性能

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摘要

Alpha-lipoic acid (ALA), a multifunctional antioxidant, can promote fatty acid mobilization, energy expenditure and scavenge free radicals. The effects of dietary ALA on the reproductive performance of breeder hens were investigated in the current study. In the 5-week experiment, 180 54-week-old Qiling breeder hens were randomly divided into three treatments with five replicates and supplemented with three levels of ALA (0, 300 and 600 mg/kg) in the basic corn-soya bean meal diets. 600 mg/kg ALA treatment group (HLA) significantly improved the eggshell thickness and strength (p .05). ALA-treated groups improved egg-laying rate compared with the CON group, but with no statistically significant difference (p > .05). The levels of HDL-C, ALB and estradiol (E2) of the serum in the HLA group were elevated compared with the CON group (p .05). In addition, ALA (600 mg/kg) treatment exhibited a reduced level of serum AST and TG (p .05). Dietary ALA increased the activity of hepatic lipase in liver (p .05). Supplemental 600 mg/kg ALA also improved the SOD activity and total antioxidant capacity level, along with a decreased MDA in ovarian tissue (p .05). Furthermore, the mRNA expressions ofESR1,ESR2,VTG2andApoBin the liver andFSHRin follicles were upregulated in the HLA group (p .05). In conclusion, dietary supplementation with 600 mg/kg ALA during the late egg-laying period could improve lipid metabolism and reproductive performance of breeder hens.
机译：α-脂酸（ALA），一种多功能抗氧化剂，可促进脂肪酸动员，能量消耗和清除自由基。膳食ALA对当前研究中的膳食ALA对育种母鸡生殖性能的影响。在5周的实验中，180名54周龄Qiling Breeder母鸡随机分为三种治疗，其中五种重复，并在基本玉米酱豆粕中补充有三种Ala（0,300和600 mg / kg）饮食。 600 mg / kg Ala治疗组（HLA）显着提高了蛋壳厚度和强度（p .05）。与CON组相比，ALA治疗组改善了蛋置率，但没有统计学上显着差异（p> .05）。与CON组相比，HLA组中血清中血清HDL-C，ALB和雌二醇（E2）的水平升高（p .05）。此外，ALA（600mg / kg）处理表现出降低的血清AST和TG水平（p .05）。膳食ALA增加肝脏肝脂肪酶的活性（p .05）。补充600mg / kg Ala还改善了SOD活性和总抗氧化能力水平，以及卵巢组织中的MDA降低（p .05）。此外，在HLA基团中上调肝脏和生物素卵泡的MRNA表达，ESR2，VTG2ANDAPBIN肝脏和豆素卵泡（p .05）。总之，在晚期卵子间隔期间膳食补充剂，600毫克/千克ALA可以改善血液代谢和育种母鸡的生殖性能。

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