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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Fabrication of reactive poly(vinyl alcohol) membranes for prevention of bone cement leakage
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Fabrication of reactive poly(vinyl alcohol) membranes for prevention of bone cement leakage

机译:用于预防骨水泥泄漏的反应性聚(乙烯醇)膜的制备

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Leakage of bone cement into the spinal canal has been reported to cause many adverse effects. In this study, we designed an implantable balloon kyphoplasty material that avoids cement leakage through the formation of covalent bonds with the bone cement. For this purpose, glycidyl methacrylate (GMA) was used as a reactive functional group attached to the poly(vinyl alcohol) (PVA) membrane. The prepared membrane adhered to poly(methyl methacrylate) (PMMA)-based bone cements within 10 min, which is the time required for PMMA polymerization in the bone cement. The bonding strength between the GMA PVA membrane and the PMMA-based bone cement was higher than that for the original PVA membrane, likely because vinyl bonds form between the surface of the GMA PVA membrane and the bone cement. Since the GMA PVA membrane adhered firmly to the PMMA-based bone cement, the membrane was able to completely cover the PMMA-based bone cement. (C) 2014 Wiley Periodicals, Inc.
机译:据报道,骨水泥渗漏到脊柱管中造成许多不利影响。 在这项研究中,我们设计了一种可植入的气球脑膜成形术材料,通过形成与骨水泥的共价键来避免水泥渗漏。 为此目的,甲基丙烯酸缩水甘油酯(GMA)用作连接到聚(乙烯醇)(PVA)膜附着的反应性官能团。 在10分钟内粘附到聚(甲基丙烯酸甲酯)(PMMA)的骨水泥中的制备膜,这是骨水泥中PMMA聚合所需的时间。 GMA PVA膜与PMMA的骨水泥之间的粘合强度高于原始PVA膜的粘合强度,可能是因为在GMA PVA膜的表面和骨水泥之间形成乙烯基键。 由于GMA PVA膜牢固地粘附到PMMA的骨水泥中,因此膜能够完全覆盖PMMA的骨水泥。 (c)2014 Wiley期刊,Inc。

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